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Causes of acquired methemoglobinemia - A retrospective study at a large academic hospital.
Toxicol Rep
June 2024
Department of Pathology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Methemoglobinemia is a potentially life-threatening condition caused by the formation of methemoglobin, a form of hemoglobin that cannot bind oxygen. While there are some rare congenital causes of methemoglobinemia, most cases are acquired from the effects of specific drugs or environmental exposures. In this retrospective study, we analyzed a large data set of whole blood samples analyzed for methemoglobin at an academic medical center in Midwestern United States that provides both pediatric and adult services.
View Article and Find Full Text PDFErroneous reduction of HbA1c levels in patients with type 2 diabetes mellitus on dapsone treatment for Hansen's disease - a single-center retrospective cohort study.
Indian J Dermatol Venereol Leprol
July 2022
Department of Endocrinology, Diabetes and Metabolism, Vellore, Tamil Nadu, India.
Background Dapsone treatment may reduce HbA1c levels in patients with diabetes. Aims To assess the prevalence and characteristics of dapsone associated reduction of HbA1c in patients with Hansen's disease. Methods A retrospective data review of outpatient and inpatient charts of consecutive patients with Hansen's disease and type 2 diabetes mellitus was conducted over two years from January 2014 to January 2016 at the Department of Dermatology, CMC Vellore, India.
View Article and Find Full Text PDFAn audit of dapsone-associated methaemoglobinaemia in renal transplant recipients.
Nephrology (Carlton)
September 2014
Department of Nephrology, The Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
Dapsone-induced methemoglobinemia: a primer for clinicians.
Ann Pharmacother
September 2011
Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Allied Health Professions, Wayne State University, Detroit, MI, USA.
Objective: To present a comprehensive review of dapsone-induced methemoglobinemia and its management.
Data Sources: Literature retrieval was accessed through MEDLINE (1966-March 2011), Cochrane Library, and EMBASE, using the terms dapsone and methemoglobinemia.
Study Selection And Data Extraction: All case reports, small case series, and randomized controlled trials published in English were evaluated.
Dapsone-associated methemoglobinemia in a patient with slow NAT2*5B haplotype and impaired cytochrome b5 reductase activity.
J Clin Pharmacol
February 2012
Department of Medical Sciences, University of Wisconsin-MadisonDivision of Hematology and Oncology, College of Medicine, University of Florida, Gainesville, Florida.
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