Background: Management of patients with co-existent coronary and carotid disease is a controversial and challenging issue. The risk for stroke after coronary artery bypass grafting (CABG) in patients with hemodynamically significant carotid stenosis is up to 30%. In these patients a common practice is to proceed first with the restoration of cerebral perfusion and then perform the coronary revascularization. The rationale is that this strategy will reduce perioperative neurological morbidity and mortality. However, what happens when the carotid procedure is acutely complicated by cardiac instability which necessitates the interruption of the carotid procedure?
Case Report: We describe a case of a patient with unstable angina and high grade asymptomatic bilateral carotid stenosis who underwent emergency combined CABG and carotid endarterectomy (CEA). Due to hemodynamic instability, ST-T changes, hypotension and bradycardia, upon completion of endarterectomy we placed a carotid shunt and the patient was put on cardiopulmonary bypass through median sternotomy. After triple CABG (duration of 90 minutes) we concluded the interrupted CEA procedure with primary closure of the carotid arteriotomy with the shunt in place. The postoperative course was uneventful and the patient was discharged after a week. In extreme cases with bilateral severe carotid stenosis and coronary artery disease where the carotid procedure should be interrupted, we suggest the use of carotid shunt which can provide adequate cerebral perfusion giving time to cardiac surgeon to perform the life saving cardiac procedure first.
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http://dx.doi.org/10.1186/1749-8090-6-33 | DOI Listing |
Cureus
November 2024
Neurosurgery, Kokura Memorial Hospital, Kitakyushu, JPN.
Carotid artery stenosis is a significant cause of ischemic stroke, often necessitating interventions like carotid artery stenting (CAS) to restore adequate blood flow. However, complications like intraprocedural arterial dissection can arise during the procedure. This report presents a case of intraprocedural arterial dissection during CAS using a CASPER Rx stent.
View Article and Find Full Text PDFNeurol Sci
December 2024
Department of Neurosurgery, Nakamura Memorial Hospital, South 1, West 14, Chuo-ku, Sapporo, Hokkaido, 060-8570, Japan.
Spontaneous thrombosis of intracranial aneurysms is rare. Spontaneous regression of unruptured small saccular aneurysms is even more rare. A 76-year-old woman with a history of hypertension and dyslipidemia was referred for evaluation of an unruptured intracranial aneurysm.
View Article and Find Full Text PDFJ Vasc Surg
December 2024
Department of Vascular Surgery, Red Cross Hospital, Athens, Greece.
Objective: The purpose of this study is to identify variables at the time of clinical presentation which place patients at higher risk for mortality following carotid endarterectomy (CEA) for symptomatic lesions. Further, this study will create a risk score for mortality within two years following CEA for symptomatic stenosis to help tailor future postoperative and long-term management by identifying patients who require heightened vigilance in postoperative care to facilitate survival.
Methods: The Vascular Quality Initiative (VQI) CEA module was queried for procedures performed for symptomatic (within 180 days) carotid bifurcation stenosis.
J Vasc Interv Radiol
December 2024
Vascular and Interventional Radiology Translational Research Lab, Mayo Clinic, Rochester, MN, USA; Department of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address:
Purpose: Describe the immunohistologic changes in arteriovenous fistula (AVF) stenosis treated using plain old balloon angioplasty (POBA) versus paclitaxel drug-coated balloons (DCB) MATERIALS AND METHODS: Castrated male Yorkshire pigs (n = 12) 4-5 months old had chronic kidney disease (CKD) induced with renal artery embolization. Twenty-eight days later, a side-to-end anastomosis was created between the left common carotid artery to ipsilateral external jugular vein. Four weeks later, a juxta anastomotic stenosis was treated with balloon angioplasty (PTA) or DCB and animals euthanized at 4 [POBA (n=6)] and 42 days [POBA (n=3) or DCB (n=3)] for histomorphometric analysis with immunohistochemical staining for CD-68 (macrophages), FSP-1 (fibroblasts), α-SMA (smooth muscle cells, SMCs), CD-31 (endothelial), proliferation (Ki-67), and apoptosis (TUNEL).
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Department of Neurology, First Medical Center of Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Background: Diabetic striatopathy (DS) is a rare disorder characterized by clinical manifestations of hemichorea, non-ketotic hyperglycemia, and high signal on T1-weighted MRI or high density on CT scan in basal ganglia, typically associated with poor glycemic control.
Objective: This study aimed to analyze clinical characteristics of patients with diabetic striatopathy to raise awareness amongst physicians, especially endocrinologists, about this rare neurological manifestation in patients with diabetes.
Methods: We retrospectively analyzed the data on clinical presentations, laboratory workups, and cranial CT and MRI of six patients with DS who were admitted to our hospital from October 2013 to June 2022.
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