Our purpose was to evaluate the usefulness of digital magnification mammography with matched incident exposure by investigating the physical imaging properties and doing an observer performance test. A computed radiography system and a mammographic unit were used in this study. Contact and magnification radiographies of 1.2-1.8 in combination with focal spot sizes of 0.1 mm without grid and 0.3 mm with grid were performed. Physical imaging properties, namely, scatter fraction, total modulation transfer function (MTF) including the presampled MTF and the MTF of focal spot size, and Wiener spectrum (WS), were measured. Detail visibility was evaluated by use of free-response receiver operating characteristic analysis of the detectability of simulated microcalcifications. Scatter fractions decreased considerably as the magnification factor increased without grid technique. In the grid technique, scatter fractions for all magnification techniques were comparable. The total MTFs of magnification techniques with a focal spot size of 0.1 mm improved significantly compared with the conventional contact technique. However, the improvement of the total MTFs of magnification techniques with the combination of 0.3 mm focal spot size was small. The WSs degraded with an increase of the magnification factor compared with the contact technique due to the maintained exposure incident on the object. The observer performance test indicated that the 1.8 magnification technique with the 0.1 mm focal spot size provided higher detectability than did the contact technique. Digital magnification mammography under the same incident exposure conditions improved the detectability of microcalcifications.
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http://dx.doi.org/10.1007/s12194-011-0116-3 | DOI Listing |
Med Phys
January 2025
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Background: The spatial resolution of new, photon counting detector (PCD) CT scanners is limited by the size of the focal spot. Smaller, brighter focal spots would melt the tungsten focal track of a conventional X-ray source.
Purpose: To propose focal spot multiplexing (FSM), an architecture to improve the power of small focal spots and thereby enable higher resolution clinical PCD CT.
J Colloid Interface Sci
January 2025
College of Light Industry and Food Engineering, Nanjing Forestry University, Jiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources, Nanjing 210037 China. Electronic address:
Surface-enhanced Raman scattering (SERS) is a highly sensitive technology to detect target analytes. The construction of dynamic "hot-spots" represents a significant approach to enhancing detection sensitivity. Herein, a hybrid plasma platform with dynamic "hot-spots" was developed for SERS recognition based on the assembly of gold nanospheres (AuNSs) on temperature-sensitive bacterial cellulose (BC) film grafted with poly(N-isopropylacrylamide) (PNIPAM).
View Article and Find Full Text PDFPathogens
January 2025
Swedish Veterinary Agency, 751 89 Uppsala, Sweden.
During routine sampling of northern pike, a male with circular blue-metallic granular spots mainly located on the head and back was identified. Histological investigations presented multifocally thickened epidermis rich in basophilic large structures with a granulated rim and a dense, non-granulated center. Other organs showed no signs of infection.
View Article and Find Full Text PDFCancers (Basel)
January 2025
Program in Public Health, Stony Brook Medicine, Stony Brook, NY 11794, USA.
Introduction: Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the United States (U.S.).
View Article and Find Full Text PDFChildren (Basel)
January 2025
Department of Clinical Pathology Dr. Soetomo Academic Hospital, Faculty of Medicine Universitas Airlangga, Surabaya 60132, Indonesia.
(1) Background: This study is designed to establish thyroid-stimulating hormone (TSH) reference intervals tailored to different neonatal age groups and Indonesian local populations. (2) Methods: Dried blood spot neonatal TSH values, from 1 January 2022 to 31 December 2023, were used to establish the neonatal TSH reference intervals partitioned by sex, gestational age, and ethnic group at different neonatal ages. (3) Results: A significant difference in the reference intervals value was observed in sex, gestational ages, and parental ethnicity groups in different neonatal age subgroups ( < 0.
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