Purpose Of Review: In response to a considerable volume of clinical research into chronic pain in children and young people, recent systematic reviews now provide an evidence base for management. Clinicians should be aware of this evidence and areas in which evidence is lacking.
Recent Findings: There is a strong evidence base for psychological interventions in several conditions; computerized delivery with therapist support shows promise. Multidisciplinary services are required for a small cohort of patients. The role and effects of parents in their child's pain is becoming clearer; effective interventions for parents are being developed. The evidence for effective pharmacotherapy is poor, apart from the acute management of headache.
Summary: Clinicians need to be aware of the therapeutic effect of the psychosocial approach to the management of chronic pain in children and young people. Further research is required into the pharmacological and physical aspects of management, which remain important.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/SPC.0b013e328345832d | DOI Listing |
Sci Rep
January 2025
Department of Gynecology & Obstetrics, Qilu Hospital of Shandong University, Jinan, China.
Endometriosis (EM) is a chronic disease that can cause pain and infertility in patients. As is well known, immune cell infiltrations (ICIs) play important roles in the pathogenesis of EM. However, the pathogenesis and biomarkers of EM that can be used in clinical practice and their relationship with ICIs still need to be elucidated.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Anesthesiology, Cangzhou Central Hospital, Cangzhou, China.
The potential role of hydrogen sulfide (HS) in the modulation of neuropathic pain is increasingly recognized. This study investigated the therapeutic effect of intraperitoneal injection of the HS donor sodium hydrosulfide (NaHS) on neuropathic pain. Utilizing the spared nerve injury (SNI) model in mice, the research investigates the role of astrocytes and the excitatory neurotransmitter glutamate in chronic pain.
View Article and Find Full Text PDFNPJ Antimicrob Resist
May 2023
Infection, Immunity & Inflammation Department, University College London, Great Ormond Street Institute of Child Health, 30 Guilford St, London, WC1N 1EH, UK.
Oral coamoxiclav and amoxicillin, for extended dose regimens of up to 100 days, have shown benefit in the treatment of Chronic Lower Back Pain (CLBP) associated with vertebral bone oedema, known as Modic type 1 changes, which may be caused by a bacterial infection, but the magnitude of clinical improvement has been variable. The objectives of this review were to use sparse data from the literature to estimate the exposure of amoxicillin in the intervertebral disc, and to determine whether adequate antimicrobial exposure may have been achieved. Exposure to amoxicillin in herniated disc tissue was approximately 6.
View Article and Find Full Text PDFJ Physiol Sci
January 2025
Department of Autonomic Neuroscience, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakaecho, Itabashi-ku, 173-0015, Tokyo, Japan. Electronic address:
This study aimed to examine the efficacy of a 2-week self-administered gentle mechanical skin stimulation on chronic neck and shoulder discomfort. In participants (n = 12) with chronic neck and shoulder discomfort, subjective measures of pain sensation, discomfort, and difficulty in moving using a visual analog scale (VAS, 0-10) and objective measures of 12 different joint range of motions (ROMs) for the cervical and shoulder regions, using a digital goniometer, were collected before and after self-care with contact acupuncture, called microcones. The self-care for 2 weeks significantly (p < 0.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Pediatrics, All India Institute of Medical Sciences, New Delhi, Delhi, India.
Multiple chronic ulcers of the small intestine are primarily attributed to Crohn's disease. Other differential diagnoses include rare monogenic disorders caused by mutations in and , the latter responsible for chronic enteropathy associated with (CEAS), a condition mainly reported in Asian patients. We present the case of a 10-year-old girl from India with a 5-year history of abdominal pain, altered bowel habits and failure to gain weight.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!