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Targeted antimicrobial moieties (WO2010080819): patent evaluation. | LitMetric

Targeted antimicrobial moieties (WO2010080819): patent evaluation.

Expert Opin Ther Pat

Bioengineering Department, Zhejiang Traditional Chinese Medicine University, Hangzhou 310053, PR China.

Published: April 2011

The verification of refined variants of already existing medicines proved to be a breakthrough for antibiotic research. However, resistance to old and newer antibiotics among microbacillary pathogens is evolving quickly. Drug-resistant pathogens have become an important economic burden for patients. This invention (WO2010080819) provides novel targeting moieties (peptides) that specifically/preferentially bind to microorganisms. The targeting moieties can be attached to effectors to form chimeric constructs for specifically/preferentially delivering the effector to and/or into the target organism. In certain embodiments, novel antimicrobial peptides that can be used to inhibit of certain microorganisms are provided.

Download full-text PDF

Source
http://dx.doi.org/10.1517/13543776.2011.560571DOI Listing

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