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Knowledge and Attitudes of Healthcare Professionals Regarding Disabilities in Eastern India.
Cureus
December 2024
General Surgery, All India Institute of Medical Sciences, Deoghar, Deoghar, IND.
Background: Globally, a substantial portion of the population lives with significant disabilities. Despite advancements, individuals with disabilities continue to experience poorer health outcomes, often due to inadequate knowledge and attitudes among healthcare providers. This study aimed to evaluate the knowledge and attitudes of healthcare professionals regarding disabilities in a tertiary care setting.
View Article and Find Full Text PDFTransforming precision medicine: The potential of the clinical artificial intelligent single-cell framework.
Clin Transl Med
January 2025
Department of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
The editorial, "Clinical and translational mode of single-cell measurements: An artificial intelligent single-cell," introduces the innovative clinical artificial intelligence single-cell (caiSC) system, which merges AI with single-cell informatics to advance real-time diagnostics, disease monitoring, and treatment prediction. By combining clinical data and multimodal molecular inputs, caiSC facilitates personalized medicine, promising enhanced diagnostic precision and tailored therapeutic approaches. Despite its potential, caiSC lacks comprehensive data coverage across cell types and diseases, presenting challenges in data quality and model robustness.
View Article and Find Full Text PDFIdentifying fatal poisonings using child fatality review, poison centre and death certificate data in the USA.
Inj Prev
January 2025
Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Background: Three sources used for poisoning surveillance-child fatality reviews (CFRs), poison centre (PC) calls and death certificates-employ disparate data methodologies. Our study objectives were to (1) characterise the number of fatalities captured by CFRs and PC data compared with death certificates by age and (2) compare demographic and substance characteristics of fatalities captured by the three sources.
Methods: We acquired CFR data from the National Fatality Review-Case Reporting System (NFR-CRS), PC calls from the National Poison Data System (NPDS) and death certificate data from Centers for Disease Control and Prevention's Wide-ranging Online Data for Epidemiologic Research (WONDER) on poisoning fatalities among children 0-17 years old between 2005 and 2020.
A Survey of Forensic Pathologists Regarding Medicolegal Investigation of Perinatal and Stillborn Deaths.
Am J Forensic Med Pathol
November 2024
Connecticut Office of the Chief Medical Examiner, Farmington, CT.
Stillborn and perinatal deaths may be referred to medical examiners and coroners for investigation and determination of cause and/or manner of death. One of the key questions is determining a live birth from a stillbirth. We surveyed 147 forensic pathologists to assess their investigative practices for these deaths and for their ability to diagnose a live birth and a stillbirth.
View Article and Find Full Text PDFWhy CEOs need advanced education and training for optimizing decisions in the development of innovative medicinal products? justification and recommendation.
Front Pharmacol
December 2024
Charité - Universitätsmedizin Berlin, Institute of Clinical Pharmacology and Toxicology, Berlin, Germany.
Chief executives have been educated and trained how to handle business, to take executive decisions, and take care of financial and human resources in favor of the company they are leading. CEOs (chief executive officers) of innovative pharmaceutical businesses, among others, have only seldomly been trained to understand the immense time periods involved between decisions and their moment of impact, and the skills and languages used by their internal and external R&D (research and development) staff. R&D staff and regulators, however, have undergone full training, and are usually capable of understanding each other across their various specialties (among them compound finding, quality, safety, efficacy, efficiency, risk assessment and management).
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