An artificial neural network (ANN) was used to predict the biosorption of methylene blue on Spirulina sp. biomass. Genetic and anneal algorithms were tested with different quantity of neurons at the hidden layers to determine the optimal neurons in the ANN architecture. In addition, sensitivity analyses were conducted with the optimised ANN architecture for establishing which input variables (temperature, pH, and biomass dose) significantly affect the predicted data (removal efficiency or biosorption capacity). A number of isotherm models were also compared with the optimised ANN architecture. The removal efficiency or the biosorption capacity of MB on Spirulina sp. biomass was adequately predicted with the optimised ANN architecture by using the genetic algorithm with three input neurons, and 20 neurons in each one of the two hidden layers. Sensitivity analyses demonstrated that initial pH and biomass dose show a strong influence on the predicted removal efficiency or biosorption capacity, respectively. When supplying two variables to the genetic algorithm, initial pH and biomass dose improved the prediction of the output neuron (biosorption capacity or removal efficiency). The optimised ANN architecture predicted the equilibrium data 5,000 times better than the best isotherm model. These results demonstrate that ANN can be an effective way of predicting the experimental biosorption data of MB on Spirulina sp. biomass.
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http://dx.doi.org/10.2166/wst.2011.279 | DOI Listing |
Cell
January 2025
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:
A meta-genome-wide association study across eight psychiatric disorders has highlighted the genetic architecture of pleiotropy in major psychiatric disorders. However, mechanisms underlying pleiotropic effects of the associated variants remain to be explored. We conducted a massively parallel reporter assay to decode the regulatory logic of variants with pleiotropic and disorder-specific effects.
View Article and Find Full Text PDFNature
January 2025
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants of European, East Asian, African American and Latino ancestries (n = 158,036 cases with bipolar disorder, 2.
View Article and Find Full Text PDFNat Commun
January 2025
Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion, Crete, Greece.
Artificial neural networks (ANNs) are at the core of most Deep Learning (DL) algorithms that successfully tackle complex problems like image recognition, autonomous driving, and natural language processing. However, unlike biological brains who tackle similar problems in a very efficient manner, DL algorithms require a large number of trainable parameters, making them energy-intensive and prone to overfitting. Here, we show that a new ANN architecture that incorporates the structured connectivity and restricted sampling properties of biological dendrites counteracts these limitations.
View Article and Find Full Text PDFAnn Plast Surg
February 2025
From the Department of Plastic, Hand and Faciomaxillary Surgery, The Alfred, Melbourne, Australia.
Hourglass fascicular constrictions have been reported in fewer than 100 cases globally and only in the upper limb. The etiology remains unknown. Patients often present with self-limiting pain in the affected limb followed by flaccid paralysis.
View Article and Find Full Text PDFSci Rep
January 2025
Wollega University, Nekemte, Ethiopia.
This research paper presents an advanced AI-driven hybrid power quality management system for electrical railways that addresses critical challenges in 25 kV AC traction networks through a novel integration of single-phase PV-UPQC with ANN-Lyapunov control architecture. The system effectively manages voltage unbalance exceeding 2%, high THD, voltage variations of ± 10%, and poor power factor through a dual-approach methodology combining ANN-based reference signal generation with Lyapunov optimization, enabling dynamic parameter tuning and real-time load adaptation. MATLAB/Simulink simulations validate the system's superior performance, demonstrating significant improvements, including voltage unbalance reduction from 1.
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