Two new compounds from an endophytic fungus Aspergillus sp. HS-05.

J Asian Nat Prod Res

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

Published: March 2011

Two new compounds, N-[4'-hydroxy-(E)-cinnamoyl]-l-tyrosine methyl ester (1) and methyl 4-methoxy-3-(3'-hydroxy-2'-methyl)propionyloxy-benzoate (2), were isolated from EtOAc extract of the fermentation broth of the endophytic fungus Aspergillus sp. HS-05. Their structures were elucidated by NMR, IR, UV, MS, and CD methods. Compounds 1 and 2 showed no anticancer activities against HL-60 cell lines (both of IC(50)>100 μM) in vitro.

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http://dx.doi.org/10.1080/10286020.2010.550885DOI Listing

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