AI Article Synopsis
- * Testing showed that the radiotracer was over 95% pure, but further investigation linked the unexpected distribution to a cleaning solution used for the nebulizer.
- * Instead of the recommended 70% denatured ethanol for cleaning the nebulizer, a chlorine-based cleaning agent was accidentally used, which likely caused the issue.
Article Abstract
An unexpected biodistribution of nebulized Tc-99m diethylene triamine pentaacetic acid was detected after the ventilation of a patient referred for diagnosis of pulmonary embolism. Radiochemical purity testing of the stock vial showed more than 95% labelling. Further investigation indicated that the problem was possibly associated with a cleaning agent used for the nebulizer, leading to the dissociation of the Tc-99m diethylene triamine pentaacetic acid. Manufacturer's instructions for cleaning of the nebulizer specify the use of 70% denatured ethanol solution, but a chlorine-based agent had been used inadvertently.
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| http://dx.doi.org/10.1097/MNM.0b013e328345b31b | DOI Listing |
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