A reentrant orthogonal smectic-A (SmA) phase below the tilted smectic-C phase is established in a chiral liquid crystalline compound. The temperature evolution of the layer spacing confirms monolayer structure in both SmA phases, the upper SmA as well as the reentrant SmA phase. The reentrancy of the SmA phase is explained on the basis of the mean field free energy taking into account nonmonotoneous temperature dependence of the lowest term coefficient.
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http://dx.doi.org/10.1103/PhysRevE.83.020701 | DOI Listing |
Anal Chem
December 2024
Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, P. R. China.
Cellular volatile organic compound (VOC) detection is crucial for studying lung cancer biomarkers. However, the reported VOC biomarkers from the same cell line seem to be inconsistent across different research groups. It is possibly related to the variation in culture media, and the result obtained by a conventional single medium approach (SMA) depends on what medium is used in the cell experiment.
View Article and Find Full Text PDFTissue Cell
December 2024
Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China. Electronic address:
Introduction: The phenotypic transition of vascular smooth muscle cells (VSMCs) from a quiescent, contractile type to a secretory phenotype with high proliferation and mobility is a key event in vascular remodeling. PF-477736 is an ATP-competitive inhibitor of Chk1 which induces the accumulation of DNA damage by increasing the level of replicative stress, and ultimately inhibiting cell proliferation or causing cell death. Although this compound has been utilized as an anti-tumor drug, its role in vascular remodeling remains unclear.
View Article and Find Full Text PDFBioact Mater
March 2025
Department of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou, 310016, China.
Achieving scar-free skin regeneration in clinical settings presents significant challenges. Key issues such as the imbalance in macrophage phenotype transition, delayed re-epithelialization, and excessive proliferation and differentiation of fibroblasts hinder wound healing and lead to fibrotic repair. To these, we developed an active shrinkage and antioxidative hydrogel with biomimetic mechanical functions (P&G@LMs) to reshape the healing microenvironment and effectively promote skin regeneration.
View Article and Find Full Text PDFJ Neurosci
December 2024
School of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Victoria, 3800, Australia.
Secondary motor cortical regions, such as the supplementary motor area (SMA) are involved in planning and learning motor sequences, however the neurophysiological mechanisms across these secondary cortical networks remain poorly understood. In primary motor cortex, changes in excitatory and inhibitory neurotransmission (E:I balance) accompany motor sequence learning. In particular, there is an early reduction in inhibition (i.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Chemistry, College of Science, Sultan Qaboos University, P.O. Box 36, Postal Code 123, Muscat, Sultanate of Oman. Electronic address:
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