Profaning the ultimate sanctuary: HIV latency in hematopoietic stem cells.

Cell Host Microbe

School of Life Sciences and Frontiers in Genetics Program, École Polytechnique FÉdÉrale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

Published: March 2011

The early establishment of a reservoir of latently infected T cells is a sobering obstacle to HIV eradication, in spite of the efficacy of current antiretroviral therapies. That latent proviruses might also hide in multipotent hematopoietic stem cells suggests an even more formidable challenge and potentially has therapeutic implications.

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Source
http://dx.doi.org/10.1016/j.chom.2011.03.001DOI Listing

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