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Aging of plastics and microplastics in the environment: a review on influencing factors, quantification methods, challenges, and future perspectives.
Environ Sci Pollut Res Int
January 2025
IFP Énergies Nouvelles (IFPEN), Direction Sciences de La Terre Et Technologies de L'Environnement, 1 Et 4 Avenue de Bois-Préau, 92852, Rueil-Malmaison Cedex, France.
The ubiquitous presence of fragmented plastic particles needs comprehensive understanding of its fate in the environment. The long-term persistence of microplastics (MPs) in the environment is a significant threat to the ecosystem. Even though various degradation mechanisms (physical, chemical, and biological) of commonly used plastics have been demonstrated, quantifying the degradation of MPs over time to predict the consequence of plastic littering and its persistence in the environment remains a challenge.
View Article and Find Full Text PDFNew Layered Chalcogenide-Type Metal Sulfide Materials with Improved Properties for Solar Fuel Production Applications.
Small
December 2024
Instituto de Tecnología Química, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, Valencia, E-46022, Spain.
Article Synopsis
- Novel lamellar chalcogenide materials, ITQ-75, are developed from tin and zinc sulfide using hydro(solvo)thermal methods and N-heterocyclic aromatic agents.
- Characterization involved metal doping and modifying the synthesis gel’s composition to improve electronic structure and accessibility, achieving optical band gaps around 2.0 eV for effective solar fuel production.
- The optimized ITQ-75 materials exhibited high photocatalytic performance in water-splitting reactions for hydrogen generation, demonstrating efficiency levels among the best yet, confirming their potential as effective photocatalysts for solar energy applications.
Polymethoxyflavones from Gardenia oudiepe and semi-synthetic derivatives reduce nociception in mice: Evidence for the involvement of the MAPK pathway.
Biomed Pharmacother
January 2025
UMR CNRS 8038 CiTCoM, Université Paris Cité, Paris 75006, France. Electronic address:
This study explores the potential of polymethoxyflavones (PMFs) and polyacetylated flavones (PAFs) as novel analgesic and anti-inflammatory agents. Eight derivatives, isolated from Gardenia oudiepe bud exudate or semi-synthesized from commercial kaempferol, underwent evaluations in various in vivo, in vitro, and in silico models. Acetic acid-, formalin-induced pain, and hot-plate tests were conducted in mice (n = 6).
View Article and Find Full Text PDFAbscisic acid, an evolutionary conserved hormone: Biosynthesis, therapeutic and diagnostic applications in mammals.
Biochem Pharmacol
November 2024
Neurobiotecnologia Group, Institute of Advanced Materiales (INAM), Universitat Jaume I, Avda. de Vicent Sos Baynat, S/n, 12071 Castelló de La Plana, Spain. Electronic address:
Abscisic acid (ABA), a phytohormone traditionally recognized for its role in plant stress responses, has recently emerged as a significant player in mammalian defense mechanisms. Like plants, various mammalian cell types synthesize ABA in response to specific health challenges, although the precise pathways remain not fully elucidated. ABA is associated with the regulation of inflammation and insulin signaling, prompting extensive research into its potential as a therapeutic agent for various diseases.
View Article and Find Full Text PDFMolecular characterization of EcCLP1, a new putative cathepsin L protease from Echinococcus canadensis.
Parasite
July 2024
Departamento de Parasitología, Instituto Nacional de Enfermedades Infecciosas, INEI-ANLIS "Dr Carlos G. Malbrán", Av. Vélez Sársfield 563, 1282 Buenos Aires, Argentina - Laboratorio de Toxinopatología, Centro de Patología Experimental y Aplicada, Facultad de Medicina, Universidad de Buenos Aires (UBA), José E. Uriburu 950, 5to piso, 1114 Buenos Aires, Argentina.
Echinococcus granulosus sensu lato is a platyhelminth parasite and the etiological cause of cystic echinococcosis (CE), a zoonotic and neglected disease that infects animals and humans worldwide. As a part of the biological arsenal of the parasite, cathepsin L proteases are a group of proteins that are believed to be essential for parasite penetration, immune evasion, and establishment in the tissues of the host. In this work, we have cloned and sequenced a new putative cathepsin L protease from Echinococcus canadensis (EcCLP1).
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