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Improving the Outcome of Sick Children Referred from District Hospitals in and around Puducherry by Establishing a Communication Network: A Community-based Quality Improvement Initiative.
Indian J Crit Care Med
December 2024
Department of Pediatrics, Government District Headquarters Hospital, and DNB Postgraduate Teaching Institute, Cuddalore, Tamil Nadu, India.
Introduction: Transferring patients between hospitals is an important aspect and is often the weak link in the health system. Robust real-time communication before transfer may be a valuable tool to improve the emergency care of children. Our study was aimed at developing evidence for the effectiveness of efficient communication networks between a tertiary care hospital and the referring hospitals in improving patient outcomes.
View Article and Find Full Text PDFRefractory fungal infection: Three case reports highlighting good practice.
Med Mycol Case Rep
December 2024
Public Health Wales Mycology Reference Laboratory, University Hospital of Wales, Heath Park Way, CF14 4XW, Cardiff, United Kingdom.
Refractory invasive fungal disease is a significant clinical problem, with high morbidity, mortality and costs. The complex causes of refractory infection include breakthrough infection due to antifungal resistance (both innate and acquired), suboptimal therapy and impaired immune responses in critically ill or immunocompromised patients. This case series details three reports on the identification and management of refractory fungal infections, two cases of azole resistance and one case of resistant candidiasis, highlighting the importance of accurate diagnosis, monitoring, implementation of biomarkers (serological markers, PCR), antifungal susceptibility testing and antifungal stewardship to optimise management and minimise risks of emergence of drug resistance.
View Article and Find Full Text PDFUmbilical cord care practices and associated factors among mothers who gave birth in the last six months in hetosa district, Arsi zone, Ethiopia 2021: Community-based mixed design.
Heliyon
January 2025
Arsi University, Department of Midwifery, Asella, Ethiopia.
Background: Cord care is the series of steps applied to handle the umbilical cord after delivery of the newborn. Despite increasing the number of primary health facilities, unhygienic cord care remains persist.
Objective: To assess umbilical cord care practices and associated factors among mothers who gave birth in the last six months in Hetosa district, Arsi zone, Ethiopia, 2021.
A Pressing Emergency in Oncology: A Case Series of Patients With Posterior Reversible Encephalopathy Syndrome.
Cureus
December 2024
Department of General Medicine, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, IND.
Background: The defining characteristic of posterior reversible encephalopathy syndrome (PRES) is a reversible, predominantly vasogenic edema of the white matter, particularly affecting the parenchyma supplied by the posterior circulation. PRES is most commonly associated with hypertension. We present a case series of seven normotensive patients diagnosed with cancer who had posterior reversible encephalopathy syndrome.
View Article and Find Full Text PDFPathophysiology and clinical outcomes of pancytopenia in disseminated histoplasmosis: a scoping review.
Infection
January 2025
Department of Medical Microbiology and Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.
Article Synopsis
- The study explores the relationship between pancytopenia (a decrease in blood cells) and disseminated histoplasmosis, noting that this connection is rarely documented in existing literature.
- The authors reviewed 72 cases worldwide, primarily from the Americas, finding that many patients had underlying conditions, such as HIV and haemophagocytic lymphohistiocytosis.
- Recovery rates were relatively high at 73.6%, but significant mortality was attributed to diagnostic delays and complications, indicating that early recognition of pancytopenia may be crucial for better patient outcomes.
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