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http://dx.doi.org/10.1007/s00125-011-2113-9 | DOI Listing |
BMC Bioinformatics
January 2025
Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Single-cell RNA sequencing (scRNA-seq) has transformed biological research by offering new insights into cellular heterogeneity, developmental processes, and disease mechanisms. As scRNA-seq technology advances, its role in modern biology has become increasingly vital. This study explores the application of deep learning to single-cell data clustering, with a particular focus on managing sparse, high-dimensional data.
View Article and Find Full Text PDFSci Data
January 2025
Faculty of Computing, Engineering and Built Environment, Birmingham City University, Birmingham, B4 7XG, UK.
Automatic Compliance Checking (ACC) within the Architecture, Engineering, and Construction (AEC) sector necessitates automating the interpretation of building regulations to achieve its full potential. Converting textual rules into machine-readable formats is challenging due to the complexities of natural language and the scarcity of resources for advanced Machine Learning (ML). Addressing these challenges, we introduce CODE-ACCORD, a dataset of 862 sentences from the building regulations of England and Finland.
View Article and Find Full Text PDFInternet of Things (IoT) is one of the most important emerging technologies that supports Metaverse integrating process, by enabling smooth data transfer among physical and virtual domains. Integrating sensor devices, wearables, and smart gadgets into Metaverse environment enables IoT to deepen interactions and enhance immersion, both crucial for a completely integrated, data-driven Metaverse. Nevertheless, because IoT devices are often built with minimal hardware and are connected to the Internet, they are highly susceptible to different types of cyberattacks, presenting a significant security problem for maintaining a secure infrastructure.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Earth and Environmental Sciences, University of Illinois at Chicago, Chicago, IL, United States of America.
Municipal solid waste (MSW) landfills represent underexplored microbial ecosystems. Landfills contain variable amounts of antibiotic and construction and demolition (C&D) wastes, which have the potential to alter microbial metabolism due to biocidal or redox active components, and these effects are largely underexplored. To circumvent the challenge of MSW heterogeneity, we conducted a 65-day time series study on simulated MSW microcosms to assess microbiome changes using 16S rRNA sequencing in response to 1) Fe(OH)3 and 2) Na2SO4 to represent redox active components of C&D waste as well as 3) antibiotics.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Computer Science, College of Computer and Information Sciences, King Saud University, 11543, Riyadh, Saudi Arabia.
Understanding the nuanced emotions and points of view included in user-generated content remains challenging, even though text data analysis for mental health is a crucial instrument for assessing emotional well-being. Most current models neglect the significance of integrating viewpoints in comprehending mental health in favor of single-task learning. To offer a more thorough knowledge of mental health, in this study, we present an Opinion-Enhanced Hybrid BERT Model (Opinion-BERT), built to handle multi-task learning for simultaneous sentiment and status categorization.
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