AI Article Synopsis
- A new fluorescence-based method was created to visualize the production of hypochlorous acid (HOCl) induced by microbes.
- Researchers showed that the dual oxidase (DUOX) enzyme is responsible for generating HOCl in the mucosal tissue of live animals.
- This study offers new understanding of how mucosal innate immunity works in response to microbial infections.
Article Abstract
A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.
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| http://dx.doi.org/10.1039/c1cc10589b | DOI Listing |
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