AI Article Synopsis
- Researchers developed "turn-on" FRET-based luminescent probes using iridium(III) complexes to detect the amino acids cysteine (Cys) and homocysteine (Hcy).
- The study focused on how the size of the probe affects the brightness of the emitted light when detecting these amino acids.
- Findings suggest a link between the probe's steric bulk and the enhancement of emission intensity, aiding in the effective detection of Cys and Hcy.
Article Abstract
"Turn-on" FRET-based luminescent probes containing iridium(III) complexes for the detection of Cys and Hcy have been designed and synthesized. The relationship between the steric bulk of the probe and the corresponding emission intensity enhancement towards detection of Cys and Hcy has been studied.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c0cc04288a | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Luminescent Cu nanoclusters-encapsulated ZIF-8 as on-off-on fluorescent probe for efficient and selective quantification of E. coli.
Mikrochim Acta
January 2025
Department of Physics, Punjab Engineering College (Deemed to be University), Chandigarh, 160012, India.
Rapid and accurate detection of Escherichia coli (E. coli) is critical for maintaining water quality, and protecting aquatic ecosystems and public health. This research focuses on the development of a Förster resonance energy transfer (FRET)-based "turn-on" fluorescent nanosensor for real time, sensitive detection of E.
View Article and Find Full Text PDFBovine Serum Albumin-Capped Fluorescent Copper Nanocluster Incorporated with 2D-Molybdenum Disulfide Nanosheets as a FRET-Based Immune Probe for the "Turn-On" Detection of cTnT.
ACS Appl Bio Mater
January 2025
Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram, 695581 Kerala, India.
Cardiovascular disease is the primary cause of mortality worldwide, as stated by the World Health Organization. We utilized the red fluorescence emitted by copper nanoclusters (CuNCs) to detect cardiac Troponin T (cTnT). We designed a fluorescent probe to detect cTnT using an on-off-on technique.
View Article and Find Full Text PDFEngineering DNA Nanocube SAM Scaffolds for FRET-Based Biosensing: Interfacial Characterization and Sensor Demonstration.
J Am Chem Soc
November 2024
AMPEL and Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1M1,Canada.
Decorating a gold surface with molecular-level control over the positioning of DNA probes was demonstrated using a self-assembled monolayer (SAM) of wireframe DNA nanocube structures. The DNA nanocubes were specifically adsorbed and oriented using thiol-modified DNA on one face of the cube. The DNA nanocube SAM had a uniform coverage over the gold single crystal bead electrode with a separation of 20-30 nm measured by AFM.
View Article and Find Full Text PDFMolecular Weights of Polyethyleneimine-Dependent Physicochemical Tuning of Gold Nanoparticles and FRET-Based Turn-On Sensing of Polymyxin B.
Sensors (Basel)
March 2024
Joint Department of Biomedical Engineering, University of North Carolina, Chapel Hill, NC 27695, USA.
Environmental monitoring and the detection of antibiotic contaminants require expensive and time-consuming techniques. To overcome these challenges, gold nanoparticle-mediated fluorometric "turn-on" detection of Polymyxin B (PMB) in an aqueous medium was undertaken. The molecular weight of polyethyleneimine (PEI)-dependent physicochemical tuning of gold nanoparticles (PEI@AuNPs) was achieved and employed for the same.
View Article and Find Full Text PDFDevelopment of a highly sensitive fluorescent probe using (Gulmohar) tree pod shell for precise sarcosine detection in human urine samples: advancing prostate cancer diagnosis.
J Biomol Struct Dyn
January 2024
Department of Pharmaceutical Chemistry H. R. Patel Institute of Pharmaceutical Education and Research Shirpur, Maharashtra, India.
We designed a highly sensitive fluorescent sensor for the early detection of sarcosine, a potential biomarker for prostate cancer. This sensor was based on surface-cobalt-doped fluorescent carbon quantum dots (Co-CD) using a FRET-based photoluminescent sensing platform. Blue luminescent carbon quantum dots (CQD) were synthesised through a hydrothermal approach, utilizing tree pod shells.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!