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Pediatric dermatophyte onychomycosis: a review.
Int J Dermatol
September 2024
Mediprobe Research Inc., London, ON, Canada.
Article Synopsis
- * Antifungal treatments like systemic itraconazole and terbinafine show high cure rates and minimal side effects, but the limited and outdated studies reduce their reliability; topical treatments have lower cure rates but are supported by larger clinical trials.
- * Children with weakened immune systems are at higher risk and require tailored treatment; maintaining good hygiene and early intervention are essential for preventing and reducing the spread of the infection.
Top 20 Research Studies of 2023 for Primary Care Physicians.
Am Fam Physician
July 2024
University of Georgia, Athens.
This article summarizes the top 20 research studies of 2023 identified as POEMs (patient-oriented evidence that matters) and the most highly rated guidelines. A large randomized controlled trial found that the time antihypertensive medications are taken has no effect on important outcomes. A fixed-dose approach to statin prescribing is not inferior to a treat-to-target strategy for management of lipid levels.
View Article and Find Full Text PDFPathophysiology and Management of Onychomycosis and Novel Approaches for Effective Transdermal Applications.
Int J Pharm Compd
December 2023
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Kolkata, Kolkata, India.
Onychomycosis is the most common fungal nail infection accounting for 50% of nail disorders. This infection is most common in the toenails than in the nails of the fingers. It is caused by various fungal species like Trichophyton rubrum, Trichophyton mentagrophytes, Scopulariopsis brevicaulis, Aspergillus spp, Fusarium spp, Acremonium spp, Alternaria spp, and Neoscytalidium.
View Article and Find Full Text PDF[Clinical picture, causative agents and diagnostics of dermatomycoses].
Dermatologie (Heidelb)
December 2022
, Biebertal, Deutschland.
Article Synopsis
- - Dermatomycoses, caused mainly by dermatophytes, affect various body areas including skin, hair, fingernails, and toenails, impacting populations like the elderly, infants, and immunocompromised individuals more frequently.
- - Candida albicans is a key player in yeast infections, targeting intertriginous areas and leading to oral mucosal infections, especially in patients with HIV/AIDS.
- - The diagnosis of dermatophyte infections involves microscopic examination and culture, but molecular methods like PCR are increasingly considered the gold standard due to their accuracy in detecting fungal species.
[Current dermatology guidelines in Germany-selected recommendations from 2021 and 2022].
Dermatologie (Heidelb)
July 2023
Division of Evidence-Based Medicine (dEBM), Klinik für Dermatologie, Venerologie und Allergologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.
Guidelines are systematically developed decision-making aids to ensure appropriate clinical care for specific medical conditions. In Germany, dermatological guidelines are developed under the aegis of the German Dermatological Society (DDG) and the Professional Association of German Dermatologists (BVDD), while European and international guidelines are published by organisations such as the European Centre for Guidelines Development (EuroGuiDerm), founded by the European Dermatology Forum (EDF) in cooperation with the Division of Evidence-Based Medicine at Charité-Universitätsmedizin Berlin. In 2021 and 2022, the German guidelines were revised or developed on topics such as the management of anticoagulation during dermatological procedures, chronic pruritus, contact dermatitis, laser therapy of the skin, psoriasis vulgaris, rosacea, extracorporeal photopheresis, onychomycosis, mucous membrane pemphigoid and prevention of skin cancer.
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