AI Article Synopsis
- * The 2009 pTNM classification differentiates between carcinoma in situ (pT2) and direct invasion into the prostatic stroma (pT4).
- * For non-metastatic muscle invasive bladder cancer with significant lymphatic invasion, the typical treatment involves neoadjuvant chemotherapy followed by surgery, but only some patients may respond completely, allowing for a possible bladder-conserving strategy in select cases.
Article Abstract
The urothelial carcinoma of the prostate is an entity which is necessary to recognize. The infiltration of the prostatic stroma is a major prognostic factor. The 2009 pTNM classification distinguish carcinoma in situ of the urethra with involvement of prostatic acini (pT2) from direct invasion of prostatic stroma through outside involvement (pT4). In case of non metastatic muscle invasive bladder cancer with major lymphatic invasion, the standard treatment remains neoadjuvant chemotherapy followed by radical cystectomy and extended lymphadenectomy. Only some patients can hope a complete response after neoadjuvant chemotherapy. For these responders, we can sometimes discuss, at an individual level, a bladder conservative strategy with an intensive surveillance.
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| http://dx.doi.org/10.1016/S1166-7087(11)70008-2 | DOI Listing |
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