Asbestos fibres discharged as a result of machine processing of brakes, are characterized by a lowered biological activity due to the fixation layer which covers them. This has been confirmed through occupational diseases' analysis and new data on malignant neoplasms epidemiology among workers engaged in machine processing of asbestos-moulded machine parts. General mortality caused by malignant neoplasms in these groups higher than in the control group, although statistically is not significant. This necessitates further epidemiologic studies to be performed at similar plants.

Download full-text PDF

Source

Publication Analysis

Top Keywords

malignant neoplasms
12
machine processing
8
[occupational morbidity
4
morbidity mortality
4
mortality malignant
4
neoplasms persons
4
persons professionally
4
professionally exposed
4
exposed asbestos
4
asbestos dust]
4

Similar Publications

Accurate survival prediction of patients with long-bone metastases is challenging, but important for optimizing treatment. The Skeletal Oncology Research Group (SORG) machine learning algorithm (MLA) has been previously developed and internally validated to predict 90-day and 1-year survival. External validation showed promise in the United States and Taiwan.

View Article and Find Full Text PDF

Exploring the microbiome-gut-testis axis in testicular germ cell tumors.

Front Cell Infect Microbiol

January 2025

Department of Oncology, Faculty of Medicine, Comenius University, Bratislava and National Cancer Institute, Bratislava, Slovakia.

The microbiome-gut-testis axis has emerged as a significant area of interest in understanding testicular cancer, particularly testicular germ cell tumors (TGCTs), which represent the most common malignancy in young men. The interplay between the gut and testicular microbiomes is hypothesized to influence tumorigenesis and reproductive health, underscoring the complex role of microbial ecosystems in disease pathology. The microbiome-gut-testis axis encompasses complex interactions between the gut microbiome, systemic immune modulation, and the local microenvironment of the testis.

View Article and Find Full Text PDF

Colorectal cancer (CRC) is one of the most prevalent and deadly malignancies worldwide. Recently, ferroptosis, a novel form of regulated cell death characterized by iron dependency and lipid peroxidation, has garnered significant attention from researchers. The mechanisms underlying ferroptosis, including intracellular iron levels, lipid peroxidation, and antioxidant system regulation, offer new insights into cancer treatment strategies.

View Article and Find Full Text PDF

Objective: To investigate the differences of clinical characteristics and treatment outcomes between paraneoplastic neurologic syndrome (PNS) patients with one high-risk antibody and patients with two high-risk antibodies.

Methods: We retrospectively analyzed the data of 51 PNS patients with high-risk antibody. Clinical data were extracted from the patients' electronic medical records.

View Article and Find Full Text PDF

Chimeric Antigen Receptor (CAR)-T cell therapy has rapidly emerged as a groundbreaking approach in cancer treatment, particularly for hematologic malignancies. However, the application of CAR-T cell therapy in solid tumors remains challenging. This review summarized the development of CAR-T technologies, emphasized the challenges and solutions in CAR-T cell therapy for solid tumors.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!