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Revisiting the unobtrusive role of exogenous stem cells beyond neural circuits replacement in spinal cord injury repair.
Theranostics
January 2025
Department of biochemistry and molecular biology, College of Life Sciences, Central South University, Changsha, 410078, Hunan, China.
Stem cell transplantation is a promising strategy to establish neural relays in situ for spinal cord injury (SCI) repair. Recent research has reported short-term survival of exogenous cells, irrespective of immunosuppressive drugs (ISD), results in similar function recovery, though the mechanisms remain unclear. This study aims to validate this short-term repair effect and the potential mechanisms in large animals.
View Article and Find Full Text PDFAnalysis of morphology, cytotoxicity, and water content characteristics of freeze-dried amnion membrane from human and bovine.
Narra J
December 2024
Department of Polymer Science and Engineering, Chonbuk National University, Jeonju, South Korea.
Placenta tissue has biological advantages, including anti-inflammatory, anti-bacterial, anti-fibrotic formation, and immunomodulatory properties. The amnion membrane (AM) is an inner side membrane of the placenta that faces the fetus. The main sources of amnion are humans and animals, with bovine being one of the significant sources.
View Article and Find Full Text PDFAssociation between vitamin D levels with IL-6 and IL-10 in umbilical cord blood of infants.
Narra J
December 2024
Center for Preventive Medical Sciences, Chiba University, Chiba, Japan.
A worldwide issue, vitamin D deficiency affects pregnant mothers and babies everywhere, including Indonesia. It involves the adaptive immune system by controlling the production of pro-and anti-inflammatory cytokines and the balance between humoral (Th2) and cell-mediated (Th1) immunity. The aim of this study was to investigate the relationship between vitamin D and the cytokines IL-6 and IL-10 in infants.
View Article and Find Full Text PDFChallenges and strengths experienced by fetal alcohol spectrum disorder diagnostic clinics in Canada.
J Intellect Dev Disabil
September 2024
The Canada FASD Research Network, Vancouver, Canada.
Background: The Canadian fetal alcohol spectrum disorder (FASD) diagnostic guideline provides clinicians with the process and procedure to reach an accurate diagnosis. However, organisational structure, culture, and resource utilisation vary. The objectives of this study were to identify the key challenges and strengths of successful FASD diagnostic clinics.
View Article and Find Full Text PDFAn Australian online training and support program for caregivers of children and youth with Fetal Alcohol Spectrum Disorder: Families linking with families.
J Intellect Dev Disabil
June 2024
NOFASD, Perth, Australia.
Background: Australia has limited supports to help families where Fetal Alcohol Spectrum Disorder (FASD) impacts children and young people. National Organisation for Fetal Alcohol Spectrum Disorder Australia (NOFASD), in conjunction with the University of Otago, New Zealand, piloted and established a 7-week online program to assist caregivers to develop strategies and supports to help their families live well in a disabling society.
Method: The online program, Families Linking with Families (FLWF), was delivered to 88 caregivers.
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