Early in the new millennium, sepsis remains one of the most urgent problems of modern reanimatology. Endotoxin, a component of the cell wall of gram-negative bacteria is of paramount importance in the pathogenesis of sepsis. Complex intensive care for severe sepsis involves selective endotoxin hemoperfusion with Polymyxin B and Alteco LPS adsorber, which has been performed in 2 patients. This study will enable specialists to formulate their opinion as to whether it is expedient to incorporate selective endotoxin hemoperfusion into complex intensive care for severe sepsis.

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