Background: Overweight and obesity is associated with metabolic and cardiovascular complications even in children and adolescents. Obesity in childhood represents a serious health problem, as an obese child frequently remains obese subject in adulthood. Obesity is also an important early risk factor for morbidity and mortality in adulthood. The aim of this study was to follow changes in selected anthropometric parameters and cardiometabolic risks in overweight and obese adolescents in response to a 4-week spa weight management program.

Methods And Results: The studied cohort included 342 adolescents (boys, n = 121, girls, n = 221); mean age (+/- SD) 14.9 +/- 1.4 years (range 13.0 to 17.9 years) with overweight or obesity, mean BMI (+/- SD) 30.1 +/- 4.4 kg/m2 who underwent a 4-week spa weight management program. Anthropometric (body height and weight, waist circumference, sagittal abdominal diameter, total body fat and intra-abdominal fat), clinical (blood pressure) and biochemical (total cholesterol, HDL and LDL cholesterol, triglycerides, glucose, insulin) parameters were studied. All examinations were conducted before and after a 4-week weight management program. Statistical evaluation of the data was performed by ANOVA. The data are expressed as means +/- SD. In response to treatment all subjects demonstrated significant decreases in initial body weight (-6.3 +/- 2.3 %), percent of total fat (-2.7 +/- 2.5 %), percent of trunk fat (-2.5 +/- 1.5 %), degree of enlargement in visceral fat stores (-2.1 +/- 2.8), as well as reductions in waist circumference (-4.7 +/- 3.2 cm) and sagittal abdominal diameter (-1.0 +/- 1.8 cm). Positive changes in lipid profile and decrease in insulin resistance as measured by HOMA-IR were also recorded together with significant reductions in both systolic and diastolic blood pressures.

Conclusions: Short-term weight management program in adolescents led to significant reductions in body weight, trunk and visceral fat and cardiometabolic health risks.

Download full-text PDF

Source

Publication Analysis

Top Keywords

weight management
20
spa weight
12
management program
12
+/-
11
cardiometabolic health
8
health risks
8
obese adolescents
8
adolescents response
8
weight
8
overweight obesity
8

Similar Publications

Oral Biomimetic Nanotherapeutics for Ulcerative Colitis Targeted Treatment by Repairing Intestinal Epithelial Barrier and Restoring Redox Homeostasis.

ACS Appl Mater Interfaces

January 2025

Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, No. 1160 Shengli South Street, Yinchuan 750004, PR China.

The structural disruption of intestinal barrier and excessive reactive oxygen/nitrogen species (RONS) generation are two intertwined factors that drive the occurrence and development of ulcerative colitis (UC). Synchronously restoring the intestinal barrier and mitigating excess RONS is a promising strategy for UC management, but its treatment outcomes are still hindered by low drug accumulation and retention in colonic lesions. Inspired by intestine colonizing bacterium, we developed a mucoadhesive probiotic -mimic entinostat-loaded hollow mesopores prussian blue (HMPB) nanotherapeutic (AM@HMPB@E) for UC-targeted therapy via repairing intestinal barrier and scavenging RONS.

View Article and Find Full Text PDF

Introduction: Retatrutide is a novel triple hormone receptor agonist which has shown great promise in tackling obesity in preliminary trials. We did this systematic review and meta-analysis to pool the results of all available trials and ascertain its safety and efficacy in the treatment of obesity.

Material And Methods: A literature search was conducted in PubMed, Cochrane Central and Embase using appropriate search terms and randomized control trials (RCTs) were identified which reported the safety and efficacy of retatrutide.

View Article and Find Full Text PDF

Background: At present, the existing internal medicine drug treatment can alleviate the high glucose toxicity of patients to a certain extent, to explore the efficacy of laparoscopic jejunoileal side to side anastomosis in the treatment of type 2 diabetes, the report is as follows.

Aim: To investigate the effect of jejunoileal side-to-side anastomosis on metabolic parameters in patients with type 2 diabetes mellitus (T2DM).

Methods: We retrospectively analyzed the clinical data of 78 patients with T2DM who were treated jejunoileal lateral anastomosis.

View Article and Find Full Text PDF

Introduction: Managing idiopathic intracranial hypertension (IIH) is challenging due to limited treatment options. This study evaluates metformin as a potential therapy for IIH, examining its impact on disease outcomes and safety.

Methods: We performed a retrospective cohort study using the TriNetX database, covering data from 2009 to August 2024.

View Article and Find Full Text PDF

Sexual abuse is any non-consensual sexual act or behavior using force, with significant concern in "men who have sex with men" (MSM), and younger individuals. The incidence of sexually transmitted infections (STI) is also prevalent in the cases of sexual abuse in this population, showing the need for comprehensive medical and psychological intervention. This study presents a case of a 15-year-old Indonesian MSM adolescent who experienced three forced sexual intercourse with a mid-thirties male friend 6 months before the consultation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!