Almost all locomotor animals respond to visual looming or to discrete changes in optical size. The need to detect and process looming remains critically important for humans in everyday life. Road traffic statistics confirm that children up to 15 years old are overrepresented in pedestrian casualties. We demonstrate that, for a given pedestrian crossing time, vehicles traveling faster loom less than slower vehicles, which creates a dangerous illusion in which faster vehicles may be perceived as not approaching. Our results from perceptual tests of looming thresholds show strong developmental trends in sensitivity, such that children may not be able to detect vehicles approaching at speeds in excess of 20 mph. This creates a risk of injudicious road crossing in urban settings when traffic speeds are higher than 20 mph. The risk is exacerbated because vehicles moving faster than this speed are more likely to result in pedestrian fatalities.
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http://dx.doi.org/10.1177/0956797611400917 | DOI Listing |
Curr Biol
January 2025
Research Group Neurobiology of Flight Control, Max Planck Institute for Neurobiology of Behavior - caesar, 53175 Bonn, Germany. Electronic address:
Approaching threats are perceived through visual looming, a rapid expansion of an image on the retina. Visual looming triggers defensive responses such as freezing, flight, turning, or take-off in a wide variety of organisms, from mice to fish to insects. In response to looming, flies perform rapid evasive turns known as saccades.
View Article and Find Full Text PDFJ Neurophysiol
December 2024
Dept. of Biol., University of Massachusetts Amherst, , Amherst, MA.
Lab rodent species commonly used to study the visual system and its development (hamsters, rats, and mice) are crepuscular/nocturnal, altricial, and possess simpler visual systems than carnivores and primates. To widen the spectra of studied species, here we introduce an alternative model, the Chilean degu (). This diurnal, precocial Caviomorph rodent has a cone enriched, well-structured retina, and well-developed central visual projections.
View Article and Find Full Text PDFSci Adv
December 2024
Byers Eye Institute, Department of Ophthalmology, Stanford University, Palo Alto, CA 94304, USA.
Retinitis pigmentosa (RP) is characterized by degeneration of rod and cone photoreceptors that progresses to irreversible blindness. Now, there are no mutation-agnostic approaches to treat RP. Here, we utilized a single adeno-associated virus (AAV)-based CRISPR activation system to activate phosphodiesterase 6B (Pde6b) to mitigate the severe degeneration in mice.
View Article and Find Full Text PDFNat Methods
December 2024
Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA.
Small-animal virtual reality (VR) systems have become invaluable tools in neuroscience for studying complex behavior during head-fixed neural recording, but they lag behind commercial human VR systems in terms of miniaturization, immersivity and advanced features such as eye tracking. Here we present MouseGoggles, a miniature VR headset for head-fixed mice that delivers independent, binocular visual stimulation over a wide field of view while enabling eye tracking and pupillometry in VR. Neural recordings in the visual cortex validate the quality of image presentation, while hippocampal recordings, associative reward learning and innate fear responses to virtual looming stimuli demonstrate an immersive VR experience.
View Article and Find Full Text PDFBiomimetics (Basel)
October 2024
Machine Life and Intelligence Research Centre, School of Mathematics and Information Science, Guangzhou University, Guangzhou 510006, China.
Animals utilize their well-evolved dynamic vision systems to perceive and evade collision threats. Driven by biological research, bio-inspired models based on lobula giant movement detectors (LGMDs) address certain gaps in constructing artificial collision-detecting vision systems with robust selectivity, offering reliable, low-cost, and miniaturized collision sensors across various scenes. Recent progress in neuroscience has revealed the energetic advantages of dendritic arrangements presynaptic to the LGMDs, which receive contrast polarity-specific signals on separate dendritic fields.
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