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Solar dermatitis in a cynomolgus macaque (Macaca fascicularis).
Res Vet Sci
January 2025
Department of Veterinary Sciences, University of Pisa, Viale delle Piagge, 2, Pisa, 56124, Italy.
Chronic exposure to ultraviolet (UV) light can cause cutaneous damage, resulting in specific pathological changes such as actinic keratosis and dermatitis. Despite actinic dermatosis being well documented in both humans and animals, it has rarely been reported in non-human primates (NHPs). Here, we describe a case of chronic UV light exposure in cynomolgus macaque (Macaca fascicularis).
View Article and Find Full Text PDFEfficacy and tolerability of 1.6% phenol-croton peeling versus topical 5% imiquimod in the treatment of actinic cheilitis: a randomized clinical trial.
Clin Exp Dermatol
November 2024
Faculdade de Medicina de Botucatu, UNESP Medical School, Botucatu, SP, Brazil.
Background: Trials evaluating the effectiveness of topical treatments for actinic cheilitis (AC) are scarce. Despite no comparative data, phenol-croton peeling has been reported as effective in treating this condition.
Methods: An open, randomized trial was conducted to compare the effectiveness and tolerability of 1.
Biotics as novel therapeutics in targeting signs of skin ageing via the gut-skin axis.
Ageing Res Rev
December 2024
Health and Happiness (H&H) Group, H&H Research, National Food Innovation Hub, Teagasc Moorepark, Fermoy, Co., Cork P61K202, Ireland. Electronic address:
Skin ageing is a phenomenon resulting from the aggregative changes to skin structure and function and is clinically manifested by physical features such as wrinkles, hyperpigmentation, elastosis, telangiectasia, and deterioration of skin barrier integrity. One of the main drivers of skin ageing, UV radiation, negatively influences the homeostasis of cells and tissues comprising the skin by triggering production of immune-mediated reactive oxygen species (ROS) and pro-inflammatory cytokines, as well as a various hormones and neuropeptides. Interestingly, an established link between the gut and the skin coined the 'gut-skin axis' has been demonstrated, with dysbiosis and gut barrier dysfunction frequently observed in certain inflammatory skin conditions and more recently, implicated in skin ageing.
View Article and Find Full Text PDFUpper eyelid lymphatic anatomy is associated with blepharoplasty recovery.
J Plast Reconstr Aesthet Surg
December 2024
Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, 3-1-1 Asahi Matsumoto, Nagano 390-8621, Japan.
Article Synopsis
- Lymphatic vessels play a key role in wound healing and fluid absorption, and this study explored how their density in eyelid tissue affects recovery after blepharoplasty.
- The research involved 40 eyelids from 21 patients, analyzing tissue samples to determine the amounts of lymphatic vessels and elastic fibers, and assessing healing through various scales at several time points post-surgery.
- Results indicated that as patients age, lymphatic vessel density decreases, especially on the medial side of the eyelid, and higher densities correlate with better healing outcomes, particularly in reducing scarring.
Injectable Platelet-Rich Fibrin and Hyaluronic Acid Mesotherapy for Management of Actinic Elastosis of Lower Eyelids: A Case Series.
Cureus
September 2024
Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Rejuvenating the skin on the lower eyelids is often complicated. Treatment alternatives that have been practiced in the past had several complications. Additionally, they were not completely effective in addressing skin aging or actinic elastosis symptoms such as dark circles under the eyes.
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