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The clinical assessment of lung involvement in patients with Still's disease, results from the multicentre international AIDA Network Still's Disease Registry.
Rheumatology (Oxford)
January 2025
Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.
Objectives: To assess the lung involvement in patients with Still's disease, an inflammatory disease assessing both children and adults. To exploit possible associated factors for parenchymal lung involvement in these patients.
Methods: A multicentre observational study was arranged assessing consecutive patients with Still's disease characterized by the lung involvement among those included in the AIDA (AutoInflammatory Disease Alliance) Network Still's Disease Registry.
Comparative analysis of the structure and content of N-glycans from different commercial whey protein materials.
J Food Sci
January 2025
College of Food Science and Engineering, Tianjin University of Science & Technology, Tianjin, China.
Infant formulas are constantly being updated and upgraded, and N-glycans are functional glycans that have not been fully exploited to date. Commercial whey protein materials are often used as basic ingredients in infant formulas. Therefore, it is important to study N-glycans in commercial whey protein materials.
View Article and Find Full Text PDFEssential oil and furanosesquiterpenes from myrrh oleo-gum resin: a breakthrough in mosquito vector management.
Nat Prod Bioprospect
January 2025
Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032, Camerino, Italy.
Mosquitoes (Diptera: Culicidae) are vectors of various pathogens of public health concern and replacing conventional insecticides remains a challenge. In this regard, natural products represent valuable sources of potential insecticidal compounds, thus increasingly attracting research interest. Commiphora myrrha (T.
View Article and Find Full Text PDFOptimizing antibody stability and efficacy in CD47- SIRPα inhibition via computational approaches.
Mol Divers
January 2025
Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Mohali, Punjab, 160062, India.
CD47, a cell surface protein, serves as a "don't eat me" signal that prevents immune cells from engulfing healthy cells upon its interaction with SIRPα. Cancer cells exploit this mechanism by overexpressing CD47 to evade immune destruction. Blocking the interaction between CD47 and its receptor, SIRPα, is a promising therapeutic strategy.
View Article and Find Full Text PDFAn Over 30-Year Analysis of Heavy Metal Deposition in Daya Bay Sediments.
Bull Environ Contam Toxicol
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College of Marine Science, South China Agricultural University, Guangzhou, 510642, China.
Sediment cores were collected from the nearshore to bay mouth region in Daya Bay, aiming to describe the historical patterns of heavy metals deposition in the sediment. During the last 40 years, the heavy metals exhibited significant different deposition behaviors in the sediment, in which As, Zn, Cr were more enriched and contributed to metals pollution in this area. Moreover, heavy metals deposition exhibited completely opposite behaviors from the nearshore to bay mouth region.
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