During intraperitoneal administration of dispersiveness-comparable chrysotile or asbestos cement fibers to rats (20 mg thrice), mesotheliomas were found in 45.1 and 7.7% of cases respectively. Asbestos cement dust induced tumors in 2.5% of cases, which is of biological importance. Cement or freeze asbestos destruction cement dust failed to cause tumors. The latter were not detected in a control group receiving physiological saline. Asbestos cement fibers and fascicles are covered by a cement matrix. Fiber amorphization gradually occurs. In lung tissue, there may be destruction of the cement coat of fascicles and release of native chrysotile fibers that are carcinogenic.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Efficient Management of Asbestos Waste Through Utilization as Mineral Additives in Portland Cement Production.
Materials (Basel)
November 2024
Institute of Sustainable Construction, Faculty of Civil Engineering, Vilnius Gediminas Technical University, 10223 Vilnius, Lithuania.
This article presents research on the effectiveness of utilizing asbestos waste, particularly chrysotile asbestos, in the production of Portland cement. The study aimed to evaluate the feasibility of transforming asbestos cement (Eternit) through thermal treatment and its enrichment with mineral additives, enabling its integration into the clinker synthesis process. Differences in the physicochemical properties of types of cement produced from conventional raw materials and those manufactured using asbestos waste were analyzed.
View Article and Find Full Text PDFAsbestos Burden in Lungs of Subjects Deceased From Mesothelioma Who Lived in Proximity to an Asbestos Factory: A Topographic Post-Mortem SEM-EDS Study.
Am J Ind Med
November 2024
Institute for Translational Epidemiology and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Asbestos exposure and its pathological consequences, especially malignant mesothelioma (MM) still represent a major public health problem on a global scale. After the ban of asbestos in most western countries, nonoccupational exposure plays an essential role in MM pathogenesis. However, few studies have quantified asbestos lung burden after environmental exposure.
View Article and Find Full Text PDFApplication of Product of Vitrification of Asbestos-Cement Waste and CRT Glass Cullet as Reinforcing Phase in Surface Composites Produced by FSP Method.
Materials (Basel)
November 2024
Faculty of Production Engineering and Materials Technology, Department of Materials Engineering, Czestochowa University of Technology (CUT), 19 Armii Krajowej Ave., 42-200 Czestochowa, Poland.
In this study, the vitrification of asbestos-cement waste (ACW) and glass cullet from cathode-ray tubes (CRTs) was performed. The resulting product of vitrification from the abovementioned waste was used as the reinforcing phase in a composite with the AA7075 alloy matrix. The composite was made by means of the FSP (friction stir processing) method.
View Article and Find Full Text PDFGiant cell interstitial pneumonia: case series with comprehensive ultrastructural analyses of "not only" hard metal pneumoconiosis.
Histopathology
October 2024
Surgical Pathology and Cytopathology Unit, University Hospital of Padova, Padova, Italy.
Article Synopsis
- - Giant cell interstitial pneumonia (GIP) is a serious lung disease related to exposure to hard metals like tungsten, typically found in industrial tools, but it can also occur without clear exposure history.
- - In a study of five patients with GIP, researchers used advanced techniques to identify metal dust and asbestos in lung samples, finding trace amounts of tungsten and asbestos fibers associated with severe lung damage.
- - The results suggest that other factors beyond hard metal exposure might contribute to GIP's development, hinting at a complex immune mechanism that could explain its recurrence in lung transplants.
Review of epidemiological and toxicological studies on health effects from ingestion of asbestos in drinking water.
Crit Rev Toxicol
November 2024
Chemical and Product Safety, Risk Sciences International, Ottawa, ON, Canada.
Asbestos is a group of naturally occurring fibrous minerals that were commonly used in the construction of cement pipes for drinking water distribution systems. These pipes deteriorate and can release asbestos fibers into drinking water, raising concerns about potential risk to human health. The objective of this work was to synthesize human, animal, and evidence on potential health risks due to ingested asbestos in drinking water and evaluate the weight of evidence (WoE) of human health risk.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!