Objective: To optimize fertility preservation management in unilateral or bilateral testicular cancer.

Design: Case series.

Setting: Urology department and reproductive biology laboratory.

Patient(s): Dizygotic azoospermic twins presenting unilateral and bilateral synchronous testicular tumors.

Intervention(s): Testicular sperm extraction (TESE) and orchiectomy.

Main Outcome Measure(s): Semen analysis, histologic diagnosis.

Result(s): No spermatozoa were cryopreserved for the first case, because fertility preservation was proposed after orchiectomy. Spermatozoa were retrieved after TESE for his brother with bilateral tumor.

Conclusion(s): Clinicians should be aware of the need to recommend sperm banking before treatments may alter spermatogenesis. TESE may be the sole option for fertility preservation in bilateral testicular cancer.

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http://dx.doi.org/10.1016/j.fertnstert.2011.01.153DOI Listing

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