The aim of this study was to assess the cytotoxicity of orthodontic materials (brackets, wires, resin, elastomers and silver solder) using Saccharomyces cerevisiae as a model organism. The induction of cytotoxicity was assessed by two different tests using the wild-type S. cerevisiae strain FF18733: (1) direct exposure to orthodontic materials in YPD broth, and (2) exposure to artificial commercial saliva pre-treated with orthodontic materials. Only the silver solder was tested in mutant S. cerevisiae strains to investigate the origin of the observed cytotoxicity. Colony forming units per mL counts were carried out in all experiments and compared to controls to detect significant survival differences. The results showed that only the silver solder induced significant cytotoxicity, which might have occurred via oxidative stress, although this mechanism is not completely understood. Moreover, S. cerevisiae proved to be a reliable and useful model microorganism for evaluating the cytotoxicity of clinical materials.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.dental.2011.01.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Weighing up the potential of "superfoods" compounds of green tea or turmeric as adjuncts in comparison to established therapeutical approaches for periodontal disease.
Clin Oral Investig
January 2025
Clinic of Conservative and Preventive Dentistry, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.
Objective: Aim of this study was to critically appraise clinical evidence on the potential benefits of adjunctive use of superfoods green tea and turmeric as mouthrinse or local delivery agents in the treatment of periodontal disease.
Materials And Methods: Electronic searches were performed in four databases for randomized trials from inception to February 2024 assessing the supplemental use of superfoods green tea and turmeric for gingivitis/periodontitis treatment. After duplicate study selection, data extraction, and risk-of-bias assessment with the RoB 2 tool, random-effects meta-analyses of Mean Differences (MD) or Standardized Mean Differences (SMD) with their 95% confidence intervals (CI) were performed.
Three-Dimensional Assessment of the Condylar Position in Different Malocclusions Using Cone-Beam Computed Tomography: A Cross-Sectional Study.
Cureus
December 2024
Department of Orthodontics, Kothiwal Dental College and Research Centre, Moradabad, IND.
Introduction The role of the condylar position in the correct functioning of the stomatognathic system has been the center of the study. Using cone-beam computed tomography (CBCT), this study looked at the three-dimensional (3D) position of the condylar bone in patients from Class I, Class II, Division 1, and Division 2. Materials and methods This cross-sectional, retrospective study was conducted using 102 CBCT records, with 34 records allocated to each category of malocclusion classification, such as dentoskeletal Class I, skeletal Class II, and dental Class II, Division 1 and 2.
View Article and Find Full Text PDFTrueness comparison of intraoral scans for diverse arch lengths in pediatric dental models.
J Dent Sci
December 2024
School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Background/purpose: Spacing between teeth is a common trait across different stages of dentition. With the tide of the digital impression, the scanning trueness of the intraoral scanner (IOS) is a hot subject. This study aimed to determine the correlation between the level of the spaced dentition and trueness of the intraoral scanning.
View Article and Find Full Text PDFDeveloping competency-based medical education for dental education in Taiwan: A pilot study of tooth extraction entrustable professional activities.
J Dent Sci
December 2024
Department of Otolaryngology-Head and Neck Surgery, Cardinal Tien Hospital and Fu Jen Catholic University, New Taipei City, Taiwan.
Background/purpose: This study aimed to evaluate the initial implementation of competency-based medical education (CBME) through entrustable professional activities (EPAs) in Taiwan dental education, focusing on tooth extraction EPAs across undergraduate year (UGY), postgraduate year (PGY), and oral and maxillofacial surgery-residency (OS-R) levels.
Materials And Methods: Using the Delphi method, an advisory team developed and validated three levels of trial EPAs, which were implemented through the Emyway platform. A structured questionnaire was used to evaluate teachers' and students' experiences and satisfaction with Emyway and the EPAs.
The Estimation of Cementoenamel Junction Crestal Bone Distance in Mandibular Anterior Teeth.
Clin Cosmet Investig Dent
January 2025
Al-Sabah Center, Al- Yarmouk, Baghdad, Iraq.
Purpose: The study aimed to measure the distance from the cementoenamel junction (CEJ) to the alveolar bone crest on both the buccal and lingual sides of the anterior mandibular teeth utilizing cone beam computed tomography (CBCT).
Materials And Methods: Cone-beam computed tomography (CBCT) was utilized to measure the distance between CEJ and the alveolar bone crest on both the buccal and lingual sides of the mandible's anterior teeth.
Results: The mean of the distance on buccal side for the central, lateral, and canine teeth were (1.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!