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Fat Grafting With Lymphedema Fat: From Trash to Treasure?
Plast Reconstr Surg Glob Open
January 2025
From the Department of Plastic and General Surgery, Turku University Hospital, Turku, Finland.
Liposuction is a common procedure for patients with lymphedema with nonpitting adipose tissue hypertrophy. However, routinely, the lipoaspirate is discarded. Experimental studies have shown that adipose-derived stem cells in fat may enhance the regenerative and lymphangiogenic effects of the fat.
View Article and Find Full Text PDFSize Does Matter: Mastectomy Flap Thickness as an Independent Decisional Factor for the Peri-Prosthetic Device Choice in Prepectoral Breast Reconstruction.
J Clin Med
December 2024
Oncologic Breast Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
In alloplastic breast reconstruction, the choice of implant positioning and the selection of periprosthetic devices is a critical and challenging decision. Surgeons must navigate between various biologic and synthetic meshes, including acellular dermal matrices (ADM). This study aimed to propose a simple selection tool for periprosthetic devices in prepectoral breast reconstruction.
View Article and Find Full Text PDFVascular Endothelial Growth Factor Expression of Adipose-Derived Stromal Cells and Adipocytes Initiated from Fat Aspirations.
Aesthetic Plast Surg
December 2024
Institute of Pharmacology, Medical University of Vienna, Waehringerstraße 13a, 1090, Vienna, Austria.
Article Synopsis
- Fat grafting is widely used in aesthetic and reconstructive surgery but can experience complications like fat necrosis, which is influenced by factors such as fat aspiration and graft size.
- The study explored how the expression of vascular endothelial growth factor A (VEGF) and various cytokines by adipose-derived stromal cells (ADSCs) and differentiated adipocytes affects fat graft survival and angiogenesis.
- Results showed that many ADSCs have high VEGF levels, promoting tissue survival post-transfer, but differentiation into adipocytes can take time and may not provide immediate support for angiogenesis.
Breast Reconstruction-Developing a Volumetric Outcome Algorithm.
Aesthetic Plast Surg
October 2024
Sorbonne Université Paris 6, 15-21 Rue de l'École de Médecine, 75006, Paris, France.
The article by Yang et al., titled "Breast Reconstruction-Developing a Volumetric Outcome Algorithm," offers a detailed review of current research on breast volume loss, comparing various reconstruction methods and proposing strategies for optimization. The study examines the use of platelet-rich plasma (PRP) in fat transplantation, highlighting improved fat retention when PRP-enriched grafts are used.
View Article and Find Full Text PDFVolumetric evaluation of autologous fat transfer for total breast reconstruction.
J Plast Reconstr Aesthet Surg
December 2024
Department of Plastic, Reconstructive, and Hand Surgery, Maastricht University Medical Center+, Maastricht, the Netherlands; NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands; Department of Plastic, Reconstructive, and Hand Surgery, Viecuri Medical Center, Venlo, the Netherlands.
Background: Reconstructive surgeons have shifted from correcting contour irregularities using autologous fat transfer (AFT) toward reconstructing full breasts. Although several studies have researched the volumetric aspects of AFT, some outcomes such as volume retention, viability, and possible confounders for graft survival, remain unclear. This study aimed to answer these questions.
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