Objective: To evaluate the use of late first trimester maternal serum inhibin-A concentrations in prediction of preeclampsia.
Design: Prospective study.
Setting: Tanta University Hospital.
Methods: All cases (327) were subjected to complete history taking, clinical and ultrasound examination, CBC, liver function tests, estimation of 24 h urine protein and venous blood samples were taken during the late first trimester for estimation of serum level of inhibin-A.
Results: First trimester maternal serum inhibin-A concentrations were significantly higher in women who subsequently develop preeclampsia than the corresponding values in healthy matched control pregnant women.
Conclusions: Measurement of inhibin-A during late first trimester of pregnancy can be useful in the prediction of preeclampsia.
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