We propose a technique for pediatric liver transplantation that does not waste the donor's parenchyma. Organ shortage has extended criteria for donor acceptance, such that even individuals with livers of suboptimal volume can donate their segment 2-3. By incorporating wise use of parenchyma, our proposed technique for harvesting segment 2-3 for implantation in a pediatric recipient benefits these and other donors, and it might increase donations. This is especially important in countries in which procurement of organs from the deceased is not allowed. Our technique also aims to solve the problem of the large-for-size syndrome for neonates and extremely small infants and to allow for primary closure of the abdomen. This technique enables harvest of the following four grafts: (1) complete segment 2-3; (2) reduced segment 2-3; (3) complete segment 3; and (4) reduced segment 3. The surgeon will select the type that has suitable graft-to-recipient weight ratio and that suits the donor's liver anatomy and volume. These four types benefit the donor by preserving the parenchyma of segment 4 and the left part of the caudate lobe. The three graft types other than the complete segment 2-3 graft will also preserve varying fractions of the parenchyma of segment 2-3. The technique for complete segment 2-3 graft can be put into practice immediately; the techniques for the other three grafts need an imaging modality to preoperatively delineate the donor's fourth-order bile ducts. We expect to correct this deficiency in the near future by developing the requisite imaging technique.
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http://dx.doi.org/10.1002/ca.21139 | DOI Listing |
Zhongguo Gu Shang
January 2025
Department of Orthopaedics, Sir Run Run Shaw Hospital, Hangzhou 310016, Zhejiang, China.
Objective: To observe the clinical outcomes of anterior approach for the revision surgery following unsuccessful bone cement augmentation in osteoporotic vertebral compression fractures.
Methods: A total of 10 patients who experienced unsuccessful bone cement augmentation underwent anterior revision surgery between January 2020 and December 2021. There were 2 males and 8 females.
Orthop Surg
January 2025
Department of Orthopedics, The First People's Hospital of Yangquan, Yangquan, China.
Objective: High-grade dysplastic spondylolisthesis (HGDS) is a relatively rare condition mainly involving the L5/S1 segment of the spine and occurring in children and adolescents. Whether surgical fixation should be L5-S1 monosegmental or extended up to L4 remains controversial. This study aimed to compare clinical outcomes and the risk of adjacent segment spondylolisthesis between L5-S1 monosegmental fixation and L4-S1 double-segmental fixation for pediatric HGDS.
View Article and Find Full Text PDFClin Oncol (R Coll Radiol)
January 2025
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, USA.
Aim: Artificial intelligence (AI) based auto-segmentation aids radiation therapy (RT) workflows and is being adopted in clinical environments facilitated by the increased availability of commercial solutions for organs at risk (OARs). In addition, open-source imaging datasets support training for new auto-segmentation algorithms. Here, we studied if the female and male anatomies are equally represented among these solutions.
View Article and Find Full Text PDFVet Comp Orthop Traumatol
January 2025
School of Engineering, University of Guelph, Guelph, Ontario, Canada.
Objective: To determine the effect of locking head inserts (LHI) on plate strain, stiffness, and deformation when applied to a 3.5-mm broad locking compression plate (LCP) in an open fracture-gap model.
Study Design: Six, 13-hole, 3.
Med Image Anal
January 2025
School of Engineering Medicine and School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China; Key Laboratory of Big DataBased Precision Medicine (Beihang University), Ministry of Industry and Information Technology of China, Beijing, 100191, China; CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China; National Key Laboratory of Kidney Diseases, Beijing, 100853, China. Electronic address:
Precise cerebrovascular segmentation in Time-of-Flight Magnetic Resonance Angiography (TOF-MRA) data is crucial for computer-aided clinical diagnosis. The sparse distribution of cerebrovascular structures within TOF-MRA images often results in high costs for manual data labeling. Leveraging unlabeled TOF-MRA data can significantly enhance model performance.
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