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Background: Spinal cord injury (SCI) survivors with tetraplegia have great difficulty performing activities of daily living (ADLs). Functional electrical stimulation (FES) combined with exercise therapy (ET) can improve hand function, but delivering the treatment is problematic.
Objective: To compare 2 ET treatments delivered by in-home tele-therapy (IHT).
Methods: Each treatment involved ET, tele-supervised 1 h/d, 5 d/wk for 6 weeks. Treatment 1: "conventional ET" comprised strength training, computer games played with a trackball, and therapeutic electrical stimulation (TES). Treatment 2: "ReJoyce ET" comprised FES-ET on a workstation, the Rehabilitation Joystick for Computerized Exercise (ReJoyce) with which participants played computer games associated with ADLs. Participants were block-randomized into group 1 receiving conventional ET first, followed by 1-month washout, and then ReJoyce ET and group 2 in reverse order. In all, 13 participants took part, 5 completing the study with both hands, such that both groups had a sample size of 9.
Primary Outcome Measure: Action Research Arm Test (ARAT).
Secondary Outcome Measures: grasp and pinch forces and the ReJoyce automated hand function test (RAHFT).
Results: ARAT scores improved more after ReJoyce ET (13.0% ± 9.8%) than after conventional ET (4.0% ± 9.6%; F = 10.6, P < .01). RAHFT scores also improved more after ReJoyce ET (16.9% ± 8.6%) than conventional ET (3.3% ± 10.2%; F = 20.4, P < .01).
Conclusions: FES-ET on a workstation, supervised over the Internet, is feasible and may be effective for patients who can meet the residual motor function requirements of our study.
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http://dx.doi.org/10.1177/1545968310394869 | DOI Listing |
Theor Appl Genet
December 2024
Division of Feed and Livestock Research, Institute of Livestock and Grassland Science, NARO, 768 Senbonmatsu, Nasushiobara, Tochigi, 329-2793, Japan.
We have identified a unique genetic locus for seed shattering in Italian ryegrass that has an exceedingly large effect and shows partial dominance for reduced seed shattering. Genetic improvement of seed retention in forage grasses can contribute to improving their commercial seed production. The objective of this study was to identify the genetic loci responsible for seed shattering in Italian ryegrass (Lolium multiflorum Lam.
View Article and Find Full Text PDFJ Intellect Disabil Res
December 2024
Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, USA.
Background: Family caregivers of those with developmental disabilities have higher rates of depression and anxiety compared with caregivers of those without development disability. Few studies have examined factors that contribute to caregiver depression, including the appraisal of caregiving responsibilities and the physical fitness and daily function of the care recipient. The purpose of this study was to identify intrapersonal (caregiver) and interpersonal (care recipient) factors associated with depressive symptoms in caregivers of adults with Down syndrome (DS).
View Article and Find Full Text PDFDrug Dev Res
February 2025
Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, Cairo, Egypt.
New phthalazine-derived inhibitors for VEGFR-2 were synthesized for anticancer evaluations. Also, docking studies were performed to explore the suggested binding orientations of the novel derivatives inside the binding site of VEGFR-2. The achieved biological data were extremely interrelated to that of docking study.
View Article and Find Full Text PDFRSC Adv
December 2024
Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology, School of Physics and Optoelectronic Engineering, School of Environmental and Chemical Engineering, Foshan University Foshan 528000 China
Aqueous zinc-ion batteries are highly praised for their cost-effectiveness, environmental friendliness, and high safety, making them an ideal choice for next-generation energy storage systems. However, the practical application of Zn metal anodes is constrained by well-known challenges such as dendrite growth and significant interfacial side reactions. This study introduces a trace amount of taurine (TAU) as a leveling additive into the electrolyte to optimize the microstructure of the electrolyte and the anode interface chemistry.
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December 2024
Department of Human Ecology, Korea National Open University Seoul 03087 Republic of Korea
This study aimed to determine optimal washing and drying methods for maintaining the functionality of silver-coated conductive knitted fabrics, commonly used in wearable smart products. By investigating changes in the physical, chemical, and electrical properties of these fabrics under various care conditions, we sought to provide recommendations for their proper maintenance. Results showed that mechanical friction during washing, combined with the chemical effect of detergent and the effects of machine drying, led to peeling and oxidation of the silver layer, resulting in changes to the fabric's appearance, color and increased surface resistance.
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