ncIDP-assign: a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins.

Bioinformatics

Department of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.

Published: April 2011

Unlabelled: We describe here the ncIDP-assign extension for the popular NMR assignment program SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of connected resonances to the correct position in the sequence by making use of IDP random coil chemical shifts.

Availability: The ncIDP-assign extension is available at http://www.protein-nmr.org/.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065690PMC
http://dx.doi.org/10.1093/bioinformatics/btr054DOI Listing

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