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Associations between lifelong cognitive reserve, Alzheimer's disease-related plasma biomarkers, and cognitive function in dementia-free older adults: A population-based study.
J Alzheimers Dis
January 2025
Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, P.R. China.
Background: Cognitive reserve (CR), typically measured through socio-behavioral proxies, can partially explain better cognitive performance despite underlying brain aging or neuropathology.
Objective: To examine the associations of CR with mild cognitive impairment (MCI) and cognitive function while considering Alzheimer's disease (AD)-related plasma biomarkers.
Methods: This population-based cross-sectional study included 4706 dementia-free individuals from MIND-China.
Multivariate patterns among multimodal neuroimaging and clinical, cognitive, and daily functioning characteristics in bipolar disorder.
Neuropsychopharmacology
January 2025
Neurocognition and Emotion in Affective Disorders (NEAD) Centre, Psychiatric Centre Copenhagen, Mental Health Services, Capital Region of Denmark, Frederiksberg, Denmark.
Individuals with bipolar disorder (BD) show heterogeneity in clinical, cognitive, and daily functioning characteristics, which challenges accurate diagnostics and optimal treatment. A key goal is to identify brain-based biomarkers that inform patient stratification and serve as treatment targets. The objective of the present study was to apply a data-driven, multivariate approach to quantify the relationship between multimodal imaging features and behavioral phenotypes in BD.
View Article and Find Full Text PDFEMERGENT RELATIONS AND COMPETING BEHAVIOR: EFFECTS ON INTERRUPTIONS, ACCURACY AND REACTION TIME.
Behav Processes
January 2025
University of North Texas, Department of Behavior Analysis, Neurobehavioral EEG Lab. Electronic address:
This study investigated the impact of engaging in concurrent behaviors on the emergence of untrained stimulus-stimulus relations, specifically examining interruptions, accuracy, and reaction times during test. Six participants completed a computerized matching-to-sample task under three conditions: a baseline condition, a singing condition hypothesized to be incompatible with covert verbal behavior, and a foot tapping condition hypothesized to be compatible with covert verbal behavior. The tempo was kept consistent across both singing and foot tapping tasks.
View Article and Find Full Text PDFBrain Abnormalities During Self-Referential Task in Subthreshold Depression: A Near-Infrared Spectroscopy Study.
Cureus
December 2024
Department of Integrated Psychological Sciences, School of Humanities, Kwansei Gakuin University, Nishinomiya, JPN.
Background and aim Subthreshold depression is a potential risk factor for major depressive disorder. Although the neurobiological mechanism underlying major depressive disorder is well-established, the mechanism underlying subthreshold depression has not yet been fully elucidated. We investigated the characteristics of brain abnormalities in participants with subthreshold depression using near-infrared spectroscopy (NIRS) owing to its portability.
View Article and Find Full Text PDFReplicating the Expected and the Unexpected: Neuropsychological and Symptom Profiles in a Neurotypical Romanian-English Bilingual Sample.
Arch Clin Neuropsychol
January 2025
Department of Psychology, Neuropsychology Track, Windsor University, Windsor, ON N9B 3P4, Canada.
Establishing the effect of limited English proficiency (LEP) on cognitive performance within linguistically diverse populations is central to cross-cultural neuropsychological assessments. The present study was designed to replicate previous research on cognitive profiles in Romanian-English bilinguals. Seventy-six participants (54 women, MAge = 23.
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