Background: The diagnosis and management of meningioma during pregnancy is challenging, and a multidisciplinary approach is warranted. We present a case of meningioma during pregnancy with one year of follow-up.
Case: A 37-year-old, Caucasian female who presented at 28 weeks' gestation with meningioma was managed conservatively until 31.4 weeks' gestation. Worsening symptoms prompted cesarean delivery. Nine days after childbirth a craniotomy was performed due to worsening of her symptoms. Subsequent treatment included proton therapy with dramatic results.
Conclusion: The diagnosis of meningioma during pregnancy represents a challenge, with growth and regression both reported.
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Brain Spine
December 2024
Department of Gynecology, CHU de Liege, Liège, Belgium.
Introduction: Exogenous and endogenous sex hormones, especially Progesterone agonists, may be causally linked to meningioma progression. Cessation of treatment leads to stabilization or regression of Progestin-induced meningioma. In many cases, avoiding sex hormone therapy may be possible in the context of meningioma treatment.
View Article and Find Full Text PDFBMC Neurol
October 2024
Department of Neurological Surgery, Nihon University School of Medicine, 30- 1 Oyaguchikamicho, Itabashi-ku, Tokyo, 173-8610, Japan.
Background: Meningioma in the parasellar region may lead to visual impairment, so intraoperative neurological monitoring is essential for enucleation surgery. However, intraoperative neurological monitoring in pregnant women is challenging, as the anesthesia management must consider the effects and risks to the fetus. Remimazolam is a newly introduced intravenous anesthetic that has little effect on blood pressure.
View Article and Find Full Text PDFWorld Neurosurg X
January 2025
Department of Neurosurgery, Hospital de Clínicas-Universidad Nacional de Asunción, San Lorenzo, Paraguay.
SAGE Open Med Case Rep
June 2024
RCSI Department of Anaesthesia and Critical Care, Beaumont Hospital, Dublin, Ireland.
The management of intracranial malignancies in pregnancy poses unique challenges to the perioperative team. We describe the successful surgical management of a meningioma in a 28-year-old previously healthy patient, in her third trimester of pregnancy, who first presented with a generalised seizure. Without clear guidelines on the management of intracranial malignancies in pregnancy, a multidisciplinary approach was essential in providing a management plan for the patient's seizures and on the timing of her surgical intervention.
View Article and Find Full Text PDFGynecol Obstet Fertil Senol
April 2024
Service de gynécologie obstétrique, maternité Port Royal, hôpital Cochin, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France.
Maternal deaths from indirect obstetric cause result from a preexisting condition or a condition that occurred during pregnancy without obstetric causes but was aggravated by the physiological effects of pregnancy. Twenty-nine deaths with an indirect cause related to a preexisting condition, excluding circulatory diseases or infections, were analysed by the expert committee. Pre-pregnancy pathology was documented in 16 women (epilepsy, n=7; amyloid angiopathy, n=1; Dandy-Walker syndrome, n=1; autoimmune diseases, n=3; diffuse infiltrative pneumonitis, n=1; thrombotic thrombocytopenic purpura, n=1; ovarian cancer in fragile X, n=1; major sickle cell disease, n=1).
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