Tricuspid valve (TV) disease commonly occurs in combination with left-sided heart disease. Despite the growing enthusiasm for developing novel minimally invasive therapies for the mitral or aortic valve, the TV disease formerly received less attention and was frequently left untreated. Strong evidence has increased the awareness of the impact of severe TV regurgitation on patient survival, functional capacity, and surgical risk. Preoperative TV accurate description is challenging because, unlike left-sided valves, a complete visualization of tricuspid annulus and all three leaflets in one view is routinely impossible by two-dimensional transthoracic or transesophageal echocardiography. Three-dimensional echocardiography (3DE) with its unrestricted imaging capabilities has sparked significant research interest for a better understanding and improved treatment of valvular heart disease. This review summarizes the current status of 3DE for the assessment of TV morphology and function, with its clinical applications and current limitations, as well as its potential implications for designing TV repair techniques.
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http://dx.doi.org/10.1007/s11886-011-0176-3 | DOI Listing |
Eur Heart J Cardiovasc Imaging
January 2025
Radiology
January 2025
From the Department of Radiology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, No. 12 Changjia Ln, Alarm Bell St, Fucheng District, Mianyang 621000, China.
Biochim Biophys Acta Mol Basis Dis
January 2025
Department of Animal Biology, Faculty of Science, University of Málaga, Málaga, Spain; Biomedical Research Institute of Málaga and Platform on Nanomedicine (IBIMA-Plataforma BIONAND), Málaga, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Molecular markers and pathways involved in the etiology and pathophysiology of bicuspid aortopathy are poorly understood. The aim here is to delve into the molecular and cellular mechanisms of the disease and identify potential predictive molecular markers using a well-established isogenic hamster model (T-strain) of bicuspid aortic valve (BAV) and thoracic aortic dilatation (TAD). We carried out comparative quantitative proteomics combined with western blot and morpho-molecular analyses in the ascending aorta of tricuspid aortic valve (TAV) and BAV animals from the T-strain, and TAV animals from a control strain.
View Article and Find Full Text PDFJ Thorac Dis
December 2024
[This corrects the article DOI: 10.21037/jtd-22-1741.].
View Article and Find Full Text PDFBMC Cardiovasc Disord
January 2025
Department of Cardiology, Xuzhou Central Hospital, No.199 Jiefang South Road, Quanshan District, Xuzhou, 221009, People's Republic of China.
Background: The aim of this study is to identify factors associated with the development of long-term severe tricuspid regurgitation (TR) following mitral valve replacement (MVR).
Methods: A retrospective analysis was conducted involving 308 patients who underwent single-valve MVR at Xuzhou Central Hospital between April 2017 and December 2022. Preoperative color Doppler ultrasound indicated that all patients had either no or mild to moderate tricuspid regurgitation.
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