The increase in the prevalence of obesity among youth is alarming. Relationships exist between excess weight and adverse cardiometabolic markers. The aims of this study among adolescents in the Teen Eating and Activity Mentoring in Schools (TEAMS) project were to describe selected demographic characteristics, anthropometric measurements, and laboratory values of middle school students; contrast differences in rates of cardiometabolic markers for participants with body mass index (BMI) ≥ 95th percentile and <95th percentile; examine rates of exceeding cardiometabolic cutoffs by weight status; and predict the odds ratio for one or more adverse cardiometabolic outcomes when BMI ≥95th percentile. Students (N = 151) were significantly more likely to exceed cut-off points for high-density lipoprotein cholesterol (HDL-C) and blood pressure (BP) when BMI was ≥95th percentile. Students whose BMI was ≥the 95th percentile were nearly five times as likely to have the deleterious cardiometabolic outcomes of low HDL-C, high triglycerides, elevated homeostasis model assessment of insulin resistance (HOMA-IR), or elevated systolic BP than those whose BMI was
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http://dx.doi.org/10.1177/1099800410397179 DOI Listing Publication Analysis
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Introduction: This study aimed to evaluate the predictive validity and discriminatory ability of clinical outcomes, inflammatory activity, oxidative and vascular damage, and metabolic mechanisms for detecting significant improve maximum heart rate after physical activity training in individuals with psychiatric disorders and obesity comorbid using a longitudinal design and transdiagnostic perspective.
Methods: Patients with major depressive disorder, bipolar disorder and, schizophrenia and with comorbid obesity (n = 29) were assigned to a 12-week structured physical exercise program. Peripheral blood biomarkers of inflammation, oxidative stress, vascular mechanisms, and metabolic activity, as well as neurocognitive and functional performance were assessed twice, before and after intervention.
Diabetes Obes Metab
January 2025
Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.
Aims: Women with previous gestational diabetes mellitus (GDM) have an increased risk for later development of type 2 diabetes. During pregnancy, GDM affects the cardio-metabolic protein profile; however, it is unknown how GDM affects the cardio-metabolic protein profile in the long term and if it is associated with type 2 diabetes after GDM. We hypothesise that the cardio-metabolic protein profile is affected long term and is associated with the development of type 2 diabetes after GDM.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2025
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ), and University of Zurich (UZH), CH-8091 Zurich, Switzerland.
Context: Pheochromocytomas and paragangliomas (PPGLs) are rare endocrine tumors that frequently produce catecholamines. Catecholamine-induced cardiometabolic complications substantially contribute to increased morbidity and mortality in PPGL patients prior to surgical resection.
Objective: To determine whether markers of elevated cardiometabolic risk persist in patients following PPGL resection.
Hipertens Riesgo Vasc
December 2024
Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Argentina; Centro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani" CONICET-UNLP, Argentina. Electronic address:
Background: Blood pressure (BP) is linearly related to the incidence of cardiovascular disease from values as low as 115/75mmHg, even at young ages. A particularly concerning issue is the decrease representation of optimal BP among children and youth. The mechanisms by which minimal elevations in BP increase cardiovascular risk are not defined.
View Article and Find Full Text PDFJ Nutr
December 2024
Department of Diabetology, Madras Diabetes Research Foundation & Dr Mohan's Diabetes Specialties Centre, Chennai, Tamil Nadu, India. Electronic address:
Background: Asian Indians are susceptible to developing type 2 diabetes at a lower age and often consume diets that are high in glycemic load and low in healthy fats.
Objectives: This study aimed to evaluate the effect of 30 g prebreakfast and 30 g predinner supplementation of pistachios for 12 wk on glycated hemoglobin (HbA1c), other glycemic markers, anthropometry, and lipid profile of Asian Indians with prediabetes.
Methods: In a 12-wk parallel arm, randomized controlled trial, we recruited 120 participants with prediabetes based on American Diabetes Association criteria.
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