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Background And Objectives: Accurate classification of lymphadenopathy is essential for determining the pathological nature of lymph nodes (LNs), which plays a crucial role in treatment selection. The biopsy method is invasive and carries the risk of sampling failure, while the utilization of non-invasive approaches such as ultrasound can minimize the probability of iatrogenic injury and infection. With the advancement of artificial intelligence (AI) and machine learning, the diagnostic efficiency of LNs is further enhanced.

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Inpatient Pediatric Clinical Consultations to Vascular Surgery within a Children's Hospital.

J Vasc Surg

December 2024

Division of Vascular Surgery, Loma Linda School of Medicine, 11175 Campus St, Loma Linda, CA 92350, USA. Electronic address:

Article Synopsis
  • The study investigated the Vascular Surgery consults at a Children's Hospital over 4.5 years, documenting patient demographics, types of vascular issues (arterial, venous, etc.), and treatment outcomes.
  • Out of 100 consults, most cases involved acute conditions, with the majority of patients being young (average age 8.5 years), and common causes being iatrogenic injuries and trauma.
  • While many patients were managed with medical therapy, a small number required surgical interventions, and notably, no vascular-related deaths were reported in the study.
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As rates of obesity rise worldwide, incidence of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease, is increasing, worsening the burden of healthcare systems. The council of the Federation of International Societies for Pediatric Gastroenterology, Hepatology, and Nutrition (FISPGHAN) identified the topic of MASLD epidemiology, treatment, and prevention as a global priority issue to be addressed by an expert team, with the goal to describe feasible and evidence-based actions that may contribute to reducing MASLD risk. The FISPGHAN member societies nominated experts in the field.

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Objective: Ensuring uniformity of forensic medical expertise in cases related to the improper provision of medical care; reducing the load on public forensic expert institutions by reducing the number of repeated examinations; raising the authority of forensic medical expertise service via introducing a unified approach to assessing the presence and nature of cause and effect relationship.

Material And Methods: The authors provide expert and court practice examples to show fundamental differences in forensic medical assessment of causal relations of improper provision of medical care with an adverse outcome. A focus is given to the court's assessment of expert opinions in a criminal process.

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HER-2 SMASH.

Cancer Chemother Pharmacol

December 2024

Departments of Pharmacology, Medicine Faculty, Sivas Cumhuriyet University, Sivas, Türkiye.

Purpose: Human epidermal growth factor-2 (HER-2) targeted drugs are used in only HER-2 overexpressed cancers. However, only a small portion of these cancer types are HER-2 overexpressed. In this study, we aimed to upregulate HER-2 receptors in MCF-7 breast cancer and HT-29 colon cancer cell cultures, which these cells are not HER-2 upregulated in natural status.

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