The hypothalamic arcuate nucleus is a complex structure containing both orexigenic and anorexigenic neurons, coordinately regulated by leptin and energy state. In their recent Nature Neuroscience study, Aponte et al. (2011) use optogenetic technology to provide a glimpse into the consequences of exclusive activation of either NPY/AgRP or POMC neurons.
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| http://dx.doi.org/10.1016/j.cmet.2011.02.007 | DOI Listing |
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