Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/anie.201006598 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure-activity relationship study.
Dalton Trans
December 2012
Department für Chemie, Universität zu Köln, Germany.
A series of η(4)-acyloxycyclohexadiene-Fe(CO)(3) complexes was prepared and fully characterized by spectroscopic methods including single crystal X-ray diffraction. For this purpose a new synthetic access to differently acylated 1,3- and 1,5-dienol-Fe(CO)(3) complexes was developed. The enzymatically triggered CO release from these compounds was monitored (detection of CO through GC and/or by means of a myoglobin assay) and the anti-inflammatory effect of the compounds was assessed by a cellular assay based on the inhibition of NO-production by inducible NO synthase (iNOS).
View Article and Find Full Text PDFAcyloxybutadiene iron tricarbonyl complexes as enzyme-triggered CO-releasing molecules (ET-CORMs).
Angew Chem Int Ed Engl
March 2011
Department für Chemie, Universität zu Köln, Greinstrasse 4, 50939 Köln, Germany.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!