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Investigating Cell-Induced Mixing Dynamics in Microfluidic Droplets Using the Lattice Boltzmann Method.
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CNNFM Lab, School of Mechanical Engineering, College of Engineering, University of Tehran, P.O. Box 11155-4563 Tehran, Iran.
This study investigates the impact of cell dynamics on mixing efficiency within a microfluidic droplet, emphasizing the relationship between cell motion, deformability, and resultant asymmetry in velocity and concentration fields. Simulations were conducted for droplets containing encapsulated cells at varying Peclet numbers ( = 100-800) and coupling constants ( = 0.0025, 0.
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Int J Numer Method Biomed Eng
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Dipartimento di Scienze Chirurgiche Odontostomatologiche e Materno-Infantili, Università di Verona, Verona, Italy.
Accurate reconstruction of the right heart geometry and motion from time-resolved medical images is crucial for diagnostic enhancement and computational analysis of cardiac blood dynamics. Commonly used segmentation and/or reconstruction techniques, exclusively relying on short-axis cine-MRI, lack precision in critical regions of the right heart, such as the ventricular base and the outflow tract, due to its unique morphology and motion. Furthermore, the reconstruction procedure is time-consuming and necessitates significant manual intervention for generating computational domains.
View Article and Find Full Text PDFMicrofluidic Approach for Enhanced Paeoniflorin Transdermal Delivery: A Comparative Study on Different Chips and Mixing Dynamics.
AAPS PharmSciTech
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School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Paeoniflorin is a natural pharmaceutical ingredient with a widely biological activity. However, as a hydrophilic drug, the problem of low transdermal rate limits its clinical application. To overcome this shortage, LUVs were used as biocompatible carriers of paeoniflorin in this study.
View Article and Find Full Text PDFExperimental setup for labyrinth seals: Pressure, temperature, mass flow rate, rotation velocity, and pressure drop simultaneous measurement.
Rev Sci Instrum
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Department of Mechatronics and Mechanical Systems Engineering, University of São Paulo, São Paulo, SP 05508-030, Brazil.
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View Article and Find Full Text PDFHeterogeneity in definitions of surgical site infection after cranial surgery limits the validity of research findings in neurosurgery: a systematic review.
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Department of Neurosurgery, King's College Hospital, London, UK.
Surgical site infections after cranial surgery (SSI-CRAN) are serious adverse events considering the vicinity of the wound to the central nervous system. Variability in outcome definitions can hinder the ability to produce reliable evidence. This systematic review aimed to investigate whether there is variation in SSI-CRAN definitions across studies and its impact on the identification of effective treatments for patients after cranial surgery.
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