Dye-assisted internal limiting membrane (ILM) peeling and gas tamponade is the surgery of choice for idiopathic macular holes. Indocyanine green and trypan blue have been extensively used to stain the ILM. However, the retinal toxicity of indocyanine green and non-uniform staining with trypan blue has necessitated development of newer vital dyes. Brilliant blue G has recently been introduced as one such dye with adequate ILM staining and no reported retinal toxicity. We performed a 23-gauge pars plana vitrectomy with brilliant blue G-assisted ILM peeling in six patients with idiopathic macular holes, to assess the staining characteristics and short-term adverse effects of this dye. Adequate staining assisted in the complete removal of ILM and closure of macular holes in all cases. There was no evidence of intraoperative or postoperative dye-related toxicity. Brilliant blue G appears to be safe dye for ILM staining in macular hole surgery.
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http://dx.doi.org/10.4103/0301-4738.77047 | DOI Listing |
Molecules
January 2025
LSMTM, Laboratoire de Synthèse Macromoléculaire et Thio-organique Macromoléculaire, Faculty of Chemistry, University of Sciences and Technology Houari Boumediene USTHB, Algiers 16111, Algeria.
Effluents containing synthetic anionic dyes can pose a risk to ecosystems, and they must be treated before their release to the environment. Biosorption, a simple and effective process, may be a promising solution for treating these effluents. In this work, chitosan beads were crosslinked with epichlorohydrin to produce a highly stable and performant biosorbent to remove Brilliant Blue FCF dye.
View Article and Find Full Text PDFBiochem Biophys Res Commun
January 2025
Department of Cardiology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, PR China. Electronic address:
Background: Atrial fibrillation (AF) is a common cardiac arrhythmia that is characterized by atrial electrical remodeling. The P2X7 receptor (P2X7R), an ATP-gated ion channel, has been implicated in cardiovascular pathologies; however, its role in atrial electrical remodeling remains unclear. This study investigated whether inhibition of P2X7R could mitigate isoproterenol (ISO)-induced atrial electrical remodeling in rats and explored the underlying mechanisms.
View Article and Find Full Text PDFMembranes (Basel)
January 2025
Departamento de Ciencias del Agua y Medio Ambiente, Instituto Tecnológico de Sonora, 5 de Febrero 818 sur Col. Centro, Cd. Obregón C.P. 85000, Sonora, Mexico.
Technical and economic criteria were used to evaluate the feasibility of the treatment of an industrial effluent (10 m/h) for water recovery and reuse. The treatment evaluation included the following: (1) effluent characteristic determination; (2) selection and evaluation of the effluent treatment at lab scale, establishing operating conditions and process efficiency; (3) scaling up the treatment process to the industrial level; (4) treatment plant design and commercial availability analysis of the required equipment; and (5) the costs of the inversion and operation of the plant treatment, cost/m for water recovery, and time of investment recovery. The physicochemical characteristics of the effluent exposed the polluted wastewater with sodium chloride salts and colourants, predominating a mixture of tartrazine, Red 40, and brilliant blue from the synthesis of food additives.
View Article and Find Full Text PDFChemosphere
January 2025
Department of Life Science and Biochemical Engineering, Graduate School, SunMoon University, Asan, 31460, Republic of Korea; Genome-based Bio-IT Convergence Institute, Asan, 31460, Republic of Korea; Bio Big Data-based Chungnam Smart Clean Research Leader Training Program, SunMoon University, Asan, 31460, Republic of Korea; Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, Asan, 31460, Republic of Korea. Electronic address:
Laccases are of particular interest in addressing environmental challenges, such as the degradation of triphenylmethane (TPM) dyes, including crystal violet (CV) and Coomassie Brilliant Blue (CBB), which are commonly used in SDS-PAGE for protein visualization. However, these dyes present significant environmental concerns due to their resistance to degradation, which makes their removal from industrial wastewater a major challenge. To address this, the current study investigates the potential of a novel CotA laccase derived from Bacillus sp.
View Article and Find Full Text PDFJpn J Ophthalmol
January 2025
Department of Ophthalmology, Kitasato Insititute Hospital, Kitasato University, Tokyo, Japan.
Purpose: Internal limiting membrane (ILM) is usually peeled simultaneously with epiretinal membrane (ERM), however, in eyes with glaucoma and ERM, ILM is preserved in order to prevent nerve fiber damage. The aim of this study was to evaluate if a new approach for ERM is effective to keep ILM during surgery.
Study Design: Retrospective consecutive case series.
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