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Costs of Oral Corticosteroid Use in Patients with Severe Asthma With/Without Chronic Rhinosinusitis with Nasal Polyps: Data from the Italian SANI Registry.
Adv Ther
January 2025
Personalized Medicine, Asthma and Allergy, IRCCS Humanitas Clinical and Research Hospital, Via Alessandro Manzoni 56, 20089, Rozzano, MI, Italy.
Introduction: The burden of severe asthma on patients, especially on those with concomitant chronic rhinosinusitis with nasal polyps (CRSwNP), is substantial. Treatment intensification with oral corticosteroids is a common strategy for managing severe asthma exacerbations; however, prolonged exposure to systemic corticosteroids is associated with multisystem toxicity. This study aimed to quantify the association between oral corticosteroid use and annual asthma-related costs in patients with severe asthma with or without CRSwNP.
View Article and Find Full Text PDFAnalysis of shoulder motion with inertial sensors in Poland syndrome patients.
Musculoskelet Surg
December 2024
Plastic and Reconstructive Surgery Department, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Purpose: Poland syndrome is a congenital malformation characterized by agenesis or hypoplasia of pectoralis muscles. There is a limited literature on how the anatomic anomalies of PS may impact the movement of the shoulder. This study analyzes the effects of absence of the pectoralis muscles on the shoulder kinematic.
View Article and Find Full Text PDFA Spatial Multi Criteria Decision Analysis (SMCDA) to map the risk of avian influenza in Lazio and Toscana (central Italy).
Vet Ital
December 2024
Istituto Zooprofilattico Sperimentale del Lazio e della Toscana "M. Aleandri", Via Appia Nuova 1411, 00178 Roma, Italy.
Avian influenza (AI) is a global concern, affecting wild and domestic bird populations worldwide. Environmental conditions facilitating the presence of wild birds and a consistent domestic bird population contribute to the introduction and spread of AI within a territory. This study focuses on the identification of major risk areas for AI in the Lazio and Toscana Regions of central Italy using Spatial Multi-Criteria Decision Analysis (SMCDA).
View Article and Find Full Text PDFLongitudinal serological and virological survey of hepatitis E virus in wild boar (, Maremman wild boar) and fallow deer () populations in a protected area of Central Italy.
Front Vet Sci
November 2024
Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Rome, Italy.
Hepatitis E virus (HEV) is recognized as an emerging zoonosis. Pigs and wild boars are considered the main reservoirs of zoonotic HEV-3 and HEV-4 genotypes. In Europe, autochthonous human cases of hepatitis E, mainly associated with HEV-3 and consumption of raw or undercooked pig and wild boar liver/meat, have increased over the last decades.
View Article and Find Full Text PDFSerum uric acid, renal function and prognosis in patients with chronic heart failure and reduced ejection fraction. Insights from the Italian Network on Heart Failure.
Int J Cardiol
December 2024
Heart Failure Working Group, Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO), Florence, Italy.
Background: The role of hyperuricemia on short-term clinical prognosis in outpatients with heart failure and reduced ejection fraction (HFrEF) has few investigations and inconclusive results. We evaluated the prognostic impact of serum uric acid (SUA) on short-term clinical outcome among ambulatory patients with chronic HFrEF enrolled in a nationwide cardiology registry, stratified by the presence of chronic renal dysfunction (CKD).
Methods: 2246 outpatients with LVEF ≤40 %, vital status at 1-year follow-up known, and with SUA and creatinine available were stratified accordingly to SUA tertiles (≤5.
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