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Unique X-ray sheet structure of 1,8-bis(imidazolium) anthracene and its application as a fluorescent probe for DNA and DNase. | LitMetric

AI Article Synopsis

  • A new compound called imidazolium anthracene derivative 1 was created and its crystal structure was studied using X-ray techniques.
  • In water, this compound selectively reduced fluorescence when exposed to DNA, but not to other anions or nucleotides.
  • The compound was also used to observe the activity of DNase, an enzyme that digests DNA.

Article Abstract

A new imidazolium anthracene derivative 1 was synthesized, and its unique X-ray crystal structure was examined. In aqueous solutions, probe 1 exhibited a selective fluorescent quenching effect only with DNA among various anions including the nucleotides investigated. This probe was further applied to monitor the activity of DNase.

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Source
http://dx.doi.org/10.1021/ol103166qDOI Listing

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