The tracer element molten (TEM) method has been developed for flow visualization of molten Titanium in dental precision casting. The principle of this technique is as follows. When Titanium is cast, the tracer element wire inserted previously into the selective point of the sprue is molten little by little and distributed according to the molten Titanium flow in the mold cavity. After solidification, to observe the flow pattern, the tracer element needs to be analyzed on a section of the casting by EPMA equipped with the stage scan mapping system. This technique using Ag, Au, Pd or Pt as a tracer has been applied to some simple castings in shape and has been confirmed to be a very powerful technique for Titanium flow visualization in dental castings.
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Br J Hosp Med (Lond)
December 2024
Department of Neurology, Wuhan Brain Hospital, General Hospital of Yangtze River Shipping, Wuhan, Hubei, China.
Arterial spin labelling (ASL) is a non-invasive magnetic resonance imaging (MRI) method. ASL techniques can quantitatively measure cerebral perfusion by fitting a kinetic model to the difference between labelled images (tag images) and ones which are acquired without labelling (control images). ASL functional MRI (fMRI) provides quantitative perfusion maps by using arterial water as an endogenous tracer instead of depending on vascular blood oxygenation level.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA.
Manganese-52 is gaining interest as an isotope for PET imaging due to its desirable decay and chemical properties for radiopharmaceutical development. Somatostatin receptor 2 (SSTR2) is significantly overexpressed by neuroendocrine tumors (NETs) and is an important target for nuclear imaging and therapy. As an agonist, [Ga]Ga-DOTATATE has demonstrated significant internalization upon interaction with receptor ligands, whereas [Ga]Ga-DOTA-JR11(as an antagonist) exhibits limited internalization but better pharmacokinetics and increased tumor uptake.
View Article and Find Full Text PDFMethods Cell Biol
January 2025
Translational Radiomics, Luxembourg Institute of Health, Luxembourg City, Luxembourg; In-Vivo Imaging Platform, Luxembourg Institute of Health, Luxembourg City, Luxembourg.
During hypoxia, tissues are subjected to an inadequate oxygen supply, disrupting the balance needed to maintain normal function. This deficiency can occur due to reduced oxygen delivery caused by impaired blood flow or a decline in the blood's ability to carry oxygen. In tumors, hypoxia and vascularization play crucial roles, shaping their microenvironments and influencing cancer progression, response to treatment and metastatic potential.
View Article and Find Full Text PDFSci Total Environ
January 2025
Faculty of Environmental Sciences and Natural Resource Management, Norwegian University of Life Sciences, Ås, Norway.
The presence of the long-lived radionuclides Cs and Sr in ecosystems is a major environmental concern because bioavailable forms of the radionuclides are readily transferred to living organisms. The present study investigated how holometabolous insect development influences the fate of radiocaesium and radiostrontium by examining the behaviour of tracers (Cs and Sr) and stable elements during the larval feeding stage (21-23 days old), the pupal stage, and the adult stage. We aimed to evaluate the degree to which an herbivore or a detritivore food chain could serve as transfer pathways to higher trophic levels in terms of accumulation potential, and during which stage of development the accumulation potential is highest.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
Department of Chemistry and Applied Biosciences, Laboratory of Inorganic Chemistry, ETH Zürich, Vladimir-Prelog-Weg 1-5/10, Zürich, CH-8093, Switzerland; Laboratory of Radiochemistry, Centre for Nuclear Engineering and Sciences, Paul Scherrer Institute, Forschungsstrasse 111, Villigen PSI, CH-5232, Switzerland. Electronic address:
Background: The direct and accurate measurement of low-level γ-emitters in samples from nuclear facilities is a challenging task due to the presence of high activities of dominant radionuclides. In this case a complex chemical separation is required to remove interfering radionuclides prior to γ-spectrometric analysis. Several radionuclides such as, Ag, Sb, Sn and Te are of relevance for radioanalytical analysis in nuclear facilities.
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