Purpose: To report the retinal sensitivity after subthreshold diode laser micropulse photocoagulation(SDM) to evaluate its safety.
Methods: Eight eyes of 8 diabetic patients with clinically significant macular edema were treated with SDM. SDM was applied with a 15% duty cycle, 0.2 to 0.3 sec, 200 microm, at 700 to 800 mW. Postoperative retinal sensitivity (1-2 weeks) was compared to preoperative retinal sensitivity measured by microperimeter-1 (MP-1, Nidek technologies, Padova, Italy) using a 1 x 1 mm square test grid with 49 stimulus locations.
Results: The retinal sensitivity improved (more than 2 dB) in 3 eyes and remained stable (within 2 dB) in 5 eyes. The median retinal sensitivity increased significantly in 5 eyes and decreased significantly in 3 eyes. The average retinal sensitivity of 8 eyes was 12.04 +/- 3.69 dB before laser treatment, and 13.20 3.47 dB after laser treatment and there was no statistically significant change in retinal sensitivity at 2 weeks (p = 0.09).
Conclusion: Short duration SDM for diabetic macular edema has no significant effect on retinal sensitivity.
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Front Aging Neurosci
January 2025
Department of Neurology, West China Hospital of Sichuan University, Chengdu, China.
Purpose: Differentiating between Alzheimer's disease (AD) and frontotemporal dementia (FTD) can be challenging due to overlapping cognitive and behavioral manifestations. Evidence regarding non-invasive and early-stage biomarkers remains limited. Our aim was to identify retinal biomarkers for the risk of AD and FTD in populations without dementia and explore underlying brain structural mechanisms.
View Article and Find Full Text PDFDiabetes Metab Syndr Obes
January 2025
Department of Endocrinology and Metabolism, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang City, People's Republic of China.
Background/objective: Considering the uncertain relationship between high-density lipoprotein cholesterol (HDL-C) and uric acid (UA) with diabetic retinopathy (DR),this study investigates the link between Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and DR in T2DM patients, evaluating its potential for DR diagnosis and early prediction.
Study Design And Data Collection: This retrospective study analyzed 1450 type 2 diabetes patients, divided into NDR and DR groups by retinal exams. We gathered demographic and clinical data, calculated UHR, and explored its correlation with DR development.
Photodiagnosis Photodyn Ther
January 2025
Department of Ophthalmology, Ankara Bilkent City Hospital, University of Health Sciences, Ankara, Turkey.
Purpose: In this study, it was planned to compare the macular ganglion cell analysis (GCA) and peripapillary retinal nerve fiber layer (pRNFL) of the patients with preperimetric glaucoma (PPG), early stage glaucoma (EG) and the control group.
Methods: This retrospective study included a total of 103 eyes: 38 from EG patients, 30 from PPG patients, and 35 from healthy individuals at Ankara Bilkent City Hospital Glaucoma Unit between January 2018 and September 2021. Eyes were categorized into control, PPG, and EG groups based on visual field (VF) classification.
Comput Methods Programs Biomed
January 2025
Regional Institute of Ophthalmology, Indira Gandhi Institute of Medical Sciences, Patna, 800025, Bihar, India.
Background And Objectives: Hypertensive Retinopathy (HR) is a retinal manifestation resulting from persistently elevated blood pressure. Severity grading of HR is essential for patient risk stratification, effective management, progression monitoring, timely intervention, and minimizing the risk of vision impairment. Computer-aided diagnosis and artificial intelligence (AI) systems play vital roles in the diagnosis and grading of HR.
View Article and Find Full Text PDFBr J Hosp Med (Lond)
January 2025
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
The relationship between retinal fundus hemorrhage and the severity of coronary artery lesions remains unclear. This study aimed to explore the incidence of fundus hemorrhage in patients at high risk of coronary heart disease (CHD) and to examine its correlation with the SYNTAX score, a tool used to assess the complexity of coronary artery disease. This retrospective study consecutively enrolled patients undergoing coronary angiography (CAG) at Beijing Anzhen Hospital Hospital from June 2019 to January 2020.
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