Aim: To report on the changes of latency and amplitudes of the pattern VEP in patients with uncontrolled diabetes mellitus II and I before and after panretinal laser treatment.
Design: Single center hospital based comparative study.
Methods: One hundred eyes of patients with proliferative diabetic vitreoretinopathy, and HbA1C ≥ 10 percent were subjected to Pattern Visually Evoked Potentials (Medtronic keyopint system, Nicolet) prior to and 4 weeks after PRP. Results were compared to age-matched non-diabetic controls. Chi-Square test, and paired 't' test were used for statistical analysis.
Results: Preoperative mean VEP amplitude was 8.35mV±3.71, and not significantly different to the control group (mean 10.51mV±3.34) (chi square test p=1). Mean preoperative P100 latency was 106.93±7.90ms and significantly different to the control group (103.21±7.65ms) (paired t-test p=0.001). After laser treatment, VEP amplitudes decreased in 48/100 eyes (mean total 5.11mV±2.4), and P100 latency increased in 75/100 eyes (mean total 110.47±7.35ms).
Conclusion: In this study, PRP was followed by a significant decrease in VEP amplitudes in 48 percent and increase in latency in 75 percent of eyes.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038108 | PMC |
| http://dx.doi.org/10.4103/0974-9233.51992 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Binocular vision requires that the brain integrate information coming from each eye. These images are combined (fused) to generate a meaningful composite image. Differences between images, within a range, provide useful information about depth (stereopsis).
View Article and Find Full Text PDFCapacitance Measurements of Exocytosis From AII Amacrine Cells in Retinal Slices.
Bio Protoc
January 2025
Department of Biomedicine, University of Bergen, Bergen, Norway.
During neuronal synaptic transmission, the exocytotic release of neurotransmitters from synaptic vesicles in the presynaptic neuron evokes a change in conductance for one or more types of ligand-gated ion channels in the postsynaptic neuron. The standard method of investigation uses electrophysiological recordings of the postsynaptic response. However, electrophysiological recordings can directly quantify the presynaptic release of neurotransmitters with high temporal resolution by measuring the membrane capacitance before and after exocytosis, as fusion of the membrane of presynaptic vesicles with the plasma membrane increases the total capacitance.
View Article and Find Full Text PDFOptical Imaging of Trigeminal Ganglion Excitation Evoked by Electrical Stimulation of the Trigeminal Nerve.
Cureus
December 2024
Division of Dental Anesthesiology, Faculty of Dentistry Graduate School of Medicine and Dental Sciences, Niigata University, Niigata, JPN.
Background There are many reports of anatomical and physiological studies on trigeminal ganglion neurons, but few studies have analyzed temporal changes in the excitation of the trigeminal ganglion. This study aimed to establish an experimental system for spatial and temporal imaging analysis of the excitatory dynamics of trigeminal ganglion cells evoked by stimulation of a peripheral branch of the trigeminal nerve. Methods After excision of the trigeminal ganglion with the inferior alveolar nerve (IAN) from Sprague Dawley rats (seven to nine weeks old), 400-µm-thick slices of the trigeminal ganglion with the IAN were prepared.
View Article and Find Full Text PDFCross-session SSVEP brainprint recognition using attentive multi-sub-band depth identity embedding learning network.
Cogn Neurodyn
December 2025
School of Computer Science, Hangzhou Dianzi University, Hangzhou, 310018 Zhejiang China.
Brainprint recognition technology, regarded as a promising biometric technology, encounters challenges stemming from the time-varied, low signal-to-noise ratio of brain signals, such as electroencephalogram (EEG). Steady-state visual evoked potentials (SSVEP) exhibit high signal-to-noise ratio and frequency locking, making them a promising paradigm for brainprint recognition. Consequently, the extraction of time-invariant identity information from SSVEP EEG signals is essential.
View Article and Find Full Text PDFA membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina.
Nat Commun
January 2025
Center for Synaptic Neuroscience, Istituto Italiano di Tecnologia, Genova, Italy.
The lack of effective therapies for visual restoration in Retinitis pigmentosa and macular degeneration has led to the development of new strategies, such as optogenetics and retinal prostheses. However, visual restoration is poor due to the massive light-evoked activation of retinal neurons, regardless of the segregation of visual information in ON and OFF channels, which is essential for contrast sensitivity and spatial resolution. Here, we show that Ziapin2, a membrane photoswitch that modulates neuronal capacitance and excitability in a light-dependent manner, is capable of reinstating, in mouse and rat genetic models of photoreceptor degeneration, brisk and sluggish ON, OFF, and ON-OFF responses in retinal ganglion cells evoked by full-field stimuli, with reactivation of their excitatory and inhibitory conductances.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!