Background: Composite defects resulting from total parotidectomy present unique reconstructive challenges. This study reviews our experience using the anterolateral thigh (ALT) flap with adjacent fascia and nerve grafts to reconstruct these defects, and establishes a classification system and treatment algorithm that simplifies reconstruction.
Methods: Between July 2005 and November 2009, 22 patients underwent total parotidectomy and immediate reconstruction with the extended ALT flap. Of total, 21 patients had concomitant neck dissection. Defects were classified as follows: Type I, significant soft-tissue loss (n = 4); Type II, significant soft-tissue loss with facial nerve excision (n = 2); Type III, significant soft-tissue loss with resection of surrounding bone(s) (n = 5); and Type IV, significant soft-tissue loss, bone resection, and facial nerve excision (n = 11). Reconstruction procedures included free ALT (n = 9); ALT with fascia lata sling (n = 4); ALT with nerve grafting (n = 5); and ALT, fascia lata sling, and nerve grafting (n = 4). Complications, functional outcome, and patient satisfaction were assessed by chart review and prospective surveys.
Results: Fourteen of 22 patients participated in surveys. There was 1 flap loss. Donor site complications included the following: 4 patients (29%) with minor numbness of the lateral thigh skin, and 1 (7%) seroma. There was no leg weakness or infection. Recipient site morbidity included 2 patients (14%) with Frey syndrome, 3 (21%) with delayed wound healing, 5 (36%) with facial numbness, and 5 with mild oral incompetence. Smile asymmetry was present in 7 patients (50%). Ten patients (71%) reported being "very happy" with their appearance.
Conclusions: The ALT flap, used with adjacent nerve and fascia, offers a versatile option for reconstructing complex parotidectomy defects. The procedure involves minimal donor site morbidity, and results in sound functional outcomes and high degrees of patient satisfaction.
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http://dx.doi.org/10.1097/SAP.0b013e31820bcc2e | DOI Listing |
Arthroscopy
January 2025
Kansas City Orthopedic Alliance, 10777 Nall Avenue, Overland Park, KS 66224. Electronic address:
As surgeons, we strive to recognize and correct any mistakes that may occur before completing an operation, and importantly, do our best to avoid irreversible mistakes. Over-resection of the femoral cam lesion in patients having hip arthroscopy for femoroacetabular impingement syndrome has been considered irreversible. While cam under-resection is a technical complication of femoroacetabular impingement surgery to be avoided, avoiding this at the expense of over-resection of the proximal femur is of great concern.
View Article and Find Full Text PDFBr J Ophthalmol
January 2025
Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, Hong Kong
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Study Populations: Consecutive patients with TED presented to the Thyroid Eye Clinic (TEC), the Chinese University of Hong Kong between 2014 and 2023.
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J Craniofac Surg
January 2025
Department of Plastic, Reconstructive, and Aesthetic Surgery, Bilkay Clinic, Izmir, Turkey.
Advanced technology and increasing knowledge about aging faces have combined to create the illusion of thread lifting to replace surgical interventions. However, results that came far beyond expectations led to a heavy suspicion of these tools. However, combined treatments with fillers would have better outcomes with a synergetic effect.
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View Article and Find Full Text PDFCancer Sci
January 2025
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Effective therapeutic strategies for epithelioid sarcoma (EpS), a high-grade soft tissue sarcoma characterized by loss of integrase interactor 1 (INI1), have not yet been developed. The present study therefore investigated the association between INI1 loss and upregulation of the aurora kinase A (AURKA)/polo-like kinase 1 (PLK1)/cell division cycle 25C (CDC25C) axis, as well as the therapeutic relevance of this axis in EpS. Notably, our findings showed that the reintroduction of INI1 in VA-ES-BJ cells significantly reduced proliferation, mitigated tumorigenicity, and negatively regulated the expression of AURKA and its downstream effectors, as well as the activation of PLK1 and CDC25C.
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