Herein, the results of systematic mechanical property measurements of pressureless sintered calcium phosphate (CaP)-mullite composites are discussed. Our experimental results demonstrated how the mullite addition (upto 30 wt%) influenced hardness, elastic modulus, strength and toughness properties of the composites. In assessing each of these fundamental material properties, either a range of load or a number of complimentary techniques were used to obtain reliable measure of mechanical properties. Importantly, the results of single edge V notch beam measurements revealed that a reliable toughness value of ~1.5 MPa m(0.5) could be obtained in composites containing 20 or 30 wt% mullite. Our results clearly illustrated that a combination of elastic modulus (~80 GPa), compressive strength of more than 350 MPa, three-point flexural strength of 70-80 MPa, hardness of 4-5 GPa were achievable with the investigated composites. Such a combination of material properties, in addition to modest toughness property appeared to indicate that CaP-mullite composites could be used as a biomaterial for hard tissue replacement.
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http://dx.doi.org/10.1177/0885328210393292 | DOI Listing |
Int J Biol Macromol
January 2025
College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China; National Engineering Research Center for Fruit and Vegetable Processing, Key Lab of Fruit and Vegetable Processing, Ministry of Agriculture, Beijing, China.
This study utilized deep eutectic solvents (DES) based on choline chloride/lactic acid (ChCl/LA) to deconstruct coconut fibers. The effects of DES with different temperatures and molar ratios on the yield of lignin, recovery rate of residues, structural changes in lignin and solid residues, and saccharification efficiency were investigated. The results showed that acidic DES treatment effectively deconstructed the coconut fibers, resulting in a high lignin yield of 68.
View Article and Find Full Text PDFUltrasound Med Biol
January 2025
Institute of Biomedical Technologies, Auckland University of Technology, Auckland City, 1010, Auckland, New Zealand. Electronic address:
Objective: This study aims to evaluate the viability of a hypothesis for selective targeting of skin cancer cells by exploiting the spectral gap with healthy cells using analytical and numerical simulation.
Methods: The spectral gap was first identified using a viscoelastic dynamic model, with the physical and mechanical properties of healthy and cancerous skin cells deduced from previous experimental studies conducted on cell lines. The outcome of the analytical simulation was verified numerically using modal and harmonic analysis.
Int J Biol Macromol
January 2025
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren'ai Road, Industrial Park, Suzhou 215123, PR China. Electronic address:
Exogenous genes are inserted into target cells during gene therapy in order to compensate or rectify disorders brought on by faulty or aberrant genes. However, gene therapy is still in its early stages because of its unsatisfactory therapeutic effects which are mainly due to low transfection efficiency of vectors, high toxicity, and poor target specificity. A natural polymer with numerous bioactive sites, good mechanical qualities, biodegradability, biocompatibility, and processability called silk fibroin has gained attention as a possible gene therapy vector.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Departamento de Ingeniería Química, Facultad de Química, Universidad de Sevilla, 41012 Sevilla, Spain.
The current study addresses the pressing issue of unsustainable water management, particularly in regions experiencing high water stress. It focuses on examining the viability of polymeric membranes composed of biobased materials, mainly chitosan, for various sustainable water management solutions. The membranes evaluated in the study were blends of PVC with either chitosan-silica or charcoal-silica, designed to enhance their functionality and performance.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Food Packaging Technology Department, CSIR-Central Food Technological Research Institute, Mysuru, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201002, India. Electronic address:
Multifunctional PLA films were fabricated through the solution casting method by incorporating cardanol oil (CA) and amine-functionalized graphene (AFG). The effect of the CA, and AFG on the structural, mechanical, thermal, thermo-mechanical and antioxidant properties of PLA films were investigated. FTIR analysis of PLA-CA films showed distinct peak positions at 1590 cm corresponding to the aromatic CC bonds of CA, showing that CA is compatible with the PLA.
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