Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.juro.2011.01.009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mice with Reduced PAR4 Reactivity show Decreased Venous Thrombosis and Platelet Procoagulant Activity.
J Thromb Haemost
January 2025
Case Western Reserve University, School of Medicine, Department of Pharmacology, Cleveland, OH United States. Electronic address:
Background: Hypercoagulation and thrombin generation are major risk factors for venous thrombosis. Sustained thrombin signaling through PAR4 promotes platelet activation, phosphatidylserine exposure, and subsequent thrombin generation. A single-nucleotide polymorphism in PAR4 (rs2227376) changes proline to leucine extracellular loop 3 (P310L), which decreases PAR4 reactivity and is associated with a lower risk for venous thromboembolism (VTE) in a GWAS meta-analysis.
View Article and Find Full Text PDFEchocardiography in the Ventilated Patient: What the Clinician Has to Know.
J Clin Med
December 2024
Department of Cardiology, Umberto I Hospital, 84014 Nocera Inferiore, Italy.
Heart and lung sharing the same anatomical space are influenced by each other. Spontaneous breathing induces dynamic changes in intrathoracic pressure, impacting cardiac function, particularly the right ventricle. In intensive care units (ICU), mechanical ventilation (MV) and therefore positive end-expiratory pressure (PEEP) are often applied, and this inevitably influences cardiac function.
View Article and Find Full Text PDFTreatment of very high risk membranous nephropathy complicated by pulmonary embolism with glucocorticoids and rituximab: Case report.
Medicine (Baltimore)
January 2025
Division of Nephrology, Department of Medicine, National University Hospital, Singapore.
Rationale: We report the efficacy of combination prednisolone and intravenous (IV) rituximab as an immunosuppressive regimen for a young male presenting with extensive venous thromboembolism including a submassive pulmonary embolism secondary to life-threatening nephrotic syndrome from very high risk anti-phospholipase-A2 receptor (PLA2R) positive membranous nephropathy. Initial treatment was with mechanical thrombectomy and anticoagulation. Thereafter, oral prednisolone was initiated to induce remission, during a period of uninterrupted anticoagulation.
View Article and Find Full Text PDFSuccessful Treatment of an Atypical Presentation of Disseminated Retroperitoneal Seminoma: A Case Report.
HCA Healthc J Med
December 2024
Menorah Medical Center, Overland Park, KS.
Background: Testicular seminoma is the most common malignant tumor of the testis. It occurs at a rate of 5 per 100 000 men, primarily between the ages of 15 to 34. While seminomas typically occur in the testis, other primary sites include the mediastinum, the retroperitoneum, or other extra-gonadal sites.
View Article and Find Full Text PDFHybrid Setting for Minimally Invasive Mitral Surgery in Patients With Inferior Vena Caval Filters.
Ann Thorac Surg Short Rep
December 2024
Division of Cardiac Surgery, City of Health and Science (Città della Salute e della Scienza) and Department of Surgical Sciences, University of Turin, Turin, Italy.
Current cardiac surgery has evolved to include hybrid and minimally invasive settings. In parallel, less invasive techniques have been extended to complex clinical scenarios and may prove even more beneficial in higher-risk patients. However, comorbidities and challenging anatomy still represent limitations to widespread application of this philosophy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!